Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.38 |
| ▸ | AGBL2 | Q5U5Z8 | 1/20 | 0.37 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.36 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.36 |
| ▸ | FLT3 | P36888 | 1/20 | 0.35 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3231863 | 0.88 | PTGS2 (0.44) | PTGS2PTGS1ABCB11SRD5A2AKR1C3 | |
| SCHEMBL8605251 | 0.83 | MAPT (0.48) | PTGS1SRD5A2MAPK1RXFP1AKR1C3 | |
| SCHEMBL8053596 | 0.83 | GAA (0.44) | PTGS2AGBL2ABCB11SRD5A2KDM4E | |
| SCHEMBL8338116 | 0.77 | ALOX15 (0.51) | PTGS2ABCB11MEN1KMT2A | |
| SCHEMBL9724259 | 0.75 | ALDH1A1 (0.43) | SRD5A2MEN1KMT2A | |
| SCHEMBL10914752 | 0.74 | GRM5 (0.39) | GRM5PTGS2PTGS1AGBL2ABCB11 | |
| SCHEMBL3992020 | 0.73 | ALDH1A1 (0.41) | SRD5A2AKR1C3AKR1C2KDM4E | |
| SCHEMBL7674517 | 0.73 | LTA4H (0.43) | PTGDR2SRD5A2LTA4H | |
| SCHEMBL8606847 | 0.71 | HDAC6 (0.43) | MAPK1RXFP1AKR1C3TSHRMEN1 | |
| SCHEMBL11452308 | 0.71 | CXCL8 (0.44) | PTGS2PTGS1PTGDR2SRD5A2AKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5902858-A | MELT KNEADING A POLYPROYLENE RESIN, AN ISOPRENE MONOMER AND A RADICAL POLYMERIZATION INITIATOR; CLOSED-CELL FOAMS; HIGH ELONGATIONAL MELT VISCOSITY; MOLDING MATERIALS; EXPANSION; LOW DENSITY; WORKABILITY | KANEKA CORPORATION (JP) | 1999-05-11 | — | — | US | disclosed |