Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.47 |
| ▸ | FEN1 | P39748 | 1/20 | 0.47 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8341968 | 0.91 | NPC1 (0.51) | MAPTALDH1A1LMNASMN1; SMN2L3MBTL1 | |
| SCHEMBL8338779 | 0.86 | ALDH1A1 (0.64) | MAPTALDH1A1SMN1; SMN2ALOX12NPSR1 | |
| SCHEMBL8340977 | 0.83 | NPC1 (0.54) | MAPTALDH1A1LMNASMN1; SMN2L3MBTL1 | |
| SCHEMBL8335416 | 0.82 | KDM4E (0.47) | ALDH1A1LMNAPOLBKMT2AHPGD | |
| SCHEMBL8341523 | 0.82 | L3MBTL1 (0.49) | MAPTALDH1A1LMNASMN1; SMN2L3MBTL1 | |
| SCHEMBL8338985 | 0.81 | ESR2 (0.56) | MAPTALDH1A1LMNASMN1; SMN2L3MBTL1 | |
| SCHEMBL11758104 | 0.78 | MAPT (0.62) | MAPTALDH1A1LMNASMN1; SMN2L3MBTL1 | |
| SCHEMBL21852781 | 0.78 | MAPT (0.56) | MAPTALDH1A1LMNASMN1; SMN2L3MBTL1 | |
| SCHEMBL4067128 | 0.77 | ALDH1A1 (0.71) | MAPTALDH1A1LMNASMN1; SMN2GAA | |
| SCHEMBL8338666 | 0.75 | ALDH1A1 (0.60) | MAPTALDH1A1LMNASMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5968975-A | TREATING ATHEROSCLEROSIS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1999-10-19 | — | — | US | disclosed |