Bromobenzene

Bromobenzene

SCHEMBL8339717

Brc1ccccc1.OC1CCCC(O)(c2ccccc2)C1.[MgH2]

nearest known ligand 0.41

Full drug profile on Sugi Atlas →

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
OPRM1 P35372 6/20 0.40
OPRL1 P41146 6/20 0.40
OPRK1 P41145 4/20 0.40
OPRD1 P41143 3/20 0.40
ALDH1A1 P00352 1/20 0.36
TRPA1 O75762 1/20 0.36
KDM1A O60341 1/20 0.35
RCOR1 Q9UKL0 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7858287 0.91 OPRM1 (0.43) OPRM1OPRL1OPRK1OPRD1ALDH1A1
SCHEMBL8339722 0.82 OPRM1 (0.36) OPRM1OPRL1OPRK1OPRD1ALDH1A1
SCHEMBL5087603 0.74 OPRM1 (0.48) OPRM1OPRK1OPRD1
SCHEMBL11475738 0.72 TRPA1 (0.44) OPRM1OPRL1OPRK1ALDH1A1TRPA1
SCHEMBL28263872 0.72 POLB (0.38) ALDH1A1
SCHEMBL2212456 0.71 SLC6A3 (0.45) OPRM1OPRL1OPRK1OPRD1TRPA1
SCHEMBL28266017 0.71 OPRM1 (0.37) OPRM1OPRK1OPRD1ALDH1A1
SCHEMBL5087604 0.70 ALDH1A1 (0.52) OPRM1OPRL1OPRK1OPRD1ALDH1A1
SCHEMBL11815569 0.69 OPRL1 (0.50) OPRM1OPRL1OPRK1OPRD1ALDH1A1
SCHEMBL1724862 0.68 OPRL1 (0.57) OPRM1OPRL1OPRK1OPRD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0951661-A4 1999-11-17 EP disclosed
EP-0951661-A1 PROCESS AND COMPOSITION FOR GENERATING ACID POLAROID CORPORATION (US) 1999-10-27 EP disclosed
WO-1998024000-A1 PROCESS AND COMPOSITION FOR GENERATING ACID POLAROID CORPORATION (US) 1998-06-04 WO disclosed