SCHEMBL8339759

SCHEMBL8339759

CCCCC(C)(C)c1cc(N)cc(C(C)(C)C)c1O

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 3/20 0.42
CA1 P00915 2/20 0.42
LMNA P02545 3/20 0.41
RECQL P46063 1/20 0.41
ALDH1A1 P00352 5/20 0.41
POLB P06746 1/20 0.41
TYR P14679 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
TSHR P16473 3/20 0.41
KMT2A Q03164 3/20 0.41
MEN1 O00255 2/20 0.41
CYP1A2 P05177 2/20 0.41
CYP3A4 P08684 2/20 0.41
MAPK1 P28482 2/20 0.41
BLM P54132 2/20 0.41
ATM Q13315 2/20 0.41
HIF1A Q16665 2/20 0.41
NPSR1 Q6W5P4 2/20 0.41
ALOX15 P16050 2/20 0.41
GMNN O75496 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8336744 0.95 CNR2 (0.42) CA2CA1LMNARECQLALDH1A1
SCHEMBL8334497 0.90 CA2 (0.45) CA2CA1LMNARECQLALDH1A1
SCHEMBL8335913 0.84 LMNA (0.36) CA2CA1LMNARECQLALDH1A1
SCHEMBL9546274 0.83 CYP1A2 (0.35) CA2LMNARECQLALDH1A1POLB
SCHEMBL8339389 0.82 CA2 (0.48) CA2CA1LMNARECQLALDH1A1
SCHEMBL8334076 0.81 CA2 (0.47) CA2CA1LMNARECQLALDH1A1
SCHEMBL11520878 0.80 SHBG (0.34) CA2CA1LMNARECQLALDH1A1
SCHEMBL8995928 0.80 NR5A2 (0.50) CA2CA1LMNARECQLALDH1A1
SCHEMBL2802734 0.80 CA2 (0.64) CA2CA1LMNARECQLALDH1A1
SCHEMBL11867839 0.80 GABBR2 (0.47) CA2CA1LMNARECQLALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5981065-A ELECTRICAL CONDUCTORS HAVING GREASE FILLED INTERSTICES THEREBETWEEN, EACH ELECTRICAL CONDUCTOR COVERING WITH POLYOLEFINS LAYER AND THE REACTION PRODUCT OF A HINDERED AMINE AMIC ACID HYDRAZIDE, A PHENOL OR AN AMINE HYDRAZIDE UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 1999-11-09 US disclosed
WO-1993024935-A1 TELEPHONE CABLES UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 1993-12-09 WO disclosed
EP-0303986-B1 MULTIPURPOSE POLYMER BOUND STABILIZERS ATOCHEM NORTH AMERICA, INC. (US) 1992-07-29 EP disclosed
US-5096974-A Reacting primary amino or hydrazido-substituted stabilizers with maleic anhydride polymers; nonextractable and nonvolatile in polymer blends ATOCHEM NORTH AMERICA, INC. (US) 1992-03-17 US disclosed
US-4981915-A HYDRAZIDE MODIFIERS ATOCHEM NORTH AMERICA, INC. (US) 1991-01-01 US disclosed
US-4863999-A IMIDES OR AMIC ACIDS OF ANHDRIDE POLYMERS PENNWALT CORPORATION (US) 1989-09-05 US disclosed
EP-0303986-A2 Multipurpose polymer bound stabilizers ATOCHEM NORTH AMERICA, INC. (US) 1989-02-22 EP disclosed
US-4152319-A ALPHA, BETA-UNSATURATED AMIDES HAVING STERICALLY HINDERED PHENOLIC GROUP THE GOODYEAR TIRE & RUBBER COMPANY (US) 1979-05-01 US disclosed