SCHEMBL9546274

SCHEMBL9546274

CC(C)(C)CC(C)(C)c1cc(N)cc(C(C)(C)C)c1O.CCC(C)(C)c1cc(N)cc(C(C)(C)C)c1O.CCC(C)(C)c1cc(N)cc(C)c1O.CCCC(C)(C)c1cc(N)cc(C(C)(C)C)c1O.CCCC(C)(C)c1cc(N)cc(C(C)(C)CC)c1O.CCCCC(C)(C)c1cc(N)cc(C(C)(C)C)c1O.Cc1cc(N)cc(C(C)(C)C)c1O

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.35
CYP2C9 P11712 2/20 0.35
CYP2C19 P33261 2/20 0.35
ALDH1A1 P00352 2/20 0.32
CA2 P00918 1/20 0.32
POLB P06746 1/20 0.32
TYR P14679 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
LMNA P02545 2/20 0.31
RECQL P46063 1/20 0.31
CNR1 P21554 3/20 0.31
CNR2 P34972 3/20 0.31
MEN1 O00255 1/20 0.30
GMNN O75496 1/20 0.30
GABBR2 O75899 1/20 0.30
TP53 P04637 1/20 0.30
CYP3A4 P08684 1/20 0.30
ALOX15 P16050 1/20 0.30
TSHR P16473 1/20 0.30
NFKB1 P19838 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11520878 0.83 SHBG (0.34) CYP1A2CYP2C9CYP2C19ALDH1A1CA2
SCHEMBL8339759 0.83 CA2 (0.42) CYP1A2CYP2C9CYP2C19ALDH1A1CA2
SCHEMBL8334497 0.80 CA2 (0.45) CYP1A2CYP2C9CYP2C19ALDH1A1CA2
SCHEMBL8341121 0.80 LMNA (0.33) CYP1A2CYP2C9CYP2C19ALDH1A1CA2
SCHEMBL8333168 0.78 ESR1 (0.42) CYP1A2CYP2C9CYP2C19ALDH1A1CA2
SCHEMBL8334076 0.78 CA2 (0.47) CYP1A2CYP2C9CYP2C19ALDH1A1CA2
SCHEMBL8336744 0.78 CNR2 (0.42) CYP1A2CYP2C9CYP2C19ALDH1A1CA2
SCHEMBL8339389 0.77 CA2 (0.48) CYP1A2CYP2C9CYP2C19ALDH1A1CA2
SCHEMBL8335913 0.75 LMNA (0.36) CYP1A2CYP2C9CYP2C19ALDH1A1CA2
SCHEMBL8340901 0.74 SHBG (0.41) CYP1A2CYP2C9CYP2C19ALDH1A1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1993024938-A1 TELEPHONE CABLES UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 1993-12-09 WO disclosed