Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB4A | P04350 | 6/20 | 0.40 |
| ▸ | TUBB | P07437 | 6/20 | 0.40 |
| ▸ | TUBA3C | P0DPH7 | 6/20 | 0.40 |
| ▸ | TUBA1B | P68363 | 6/20 | 0.40 |
| ▸ | TUBA4A | P68366 | 6/20 | 0.40 |
| ▸ | TUBB4B | P68371 | 6/20 | 0.40 |
| ▸ | TUBB3 | Q13509 | 6/20 | 0.40 |
| ▸ | TUBB2A | Q13885 | 6/20 | 0.40 |
| ▸ | TUBB8 | Q3ZCM7 | 6/20 | 0.40 |
| ▸ | TUBA3E | Q6PEY2 | 6/20 | 0.40 |
| ▸ | TUBA1A | Q71U36 | 6/20 | 0.40 |
| ▸ | TUBA1C | Q9BQE3 | 6/20 | 0.40 |
| ▸ | TUBB6 | Q9BUF5 | 6/20 | 0.40 |
| ▸ | TUBB2B | Q9BVA1 | 6/20 | 0.40 |
| ▸ | TUBB1 | Q9H4B7 | 6/20 | 0.40 |
| ▸ | CNR2 | P34972 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8340660 | 0.85 | MAPT (0.45) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL8336291 | 0.82 | MAPT (0.43) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL8335085 | 0.82 | MAPT (0.44) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL8336809 | 0.81 | CNR2 (0.47) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL8339230 | 0.79 | TUBB4A (0.40) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL8335086 | 0.79 | CNR2 (0.36) | CNR2MAPTCYP1A2CYP2C19ALDH1A1 | |
| SCHEMBL8334430 | 0.79 | CNR2 (0.41) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL8334595 | 0.79 | CNR2 (0.39) | CNR2MAPTMEN1CYP1A2CYP2C19 | |
| SCHEMBL8337435 | 0.78 | MAPT (0.46) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL8339938 | 0.77 | PRKCZ (0.40) | CNR2MAPTKDM4EMEN1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5948796-A | OSTEOPOROSIS, CANCER, CARDIOVASCULAR DISORDERS | ELI LILLY AND COMPANY (US) | 1999-09-07 | — | — | US | disclosed |