Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HTR7 | P34969 | 6/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 2/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6746847 | 0.79 | HTR2A (0.41) | HTR2A | |
| SCHEMBL6746868 | 0.77 | DRD2 (0.39) | HTR1AHTR2A | |
| SCHEMBL6748820 | 0.76 | DPP7 (0.36) | KDM4ELMNASMN1; SMN2 | |
| SCHEMBL6751602 | 0.76 | CA12 (0.43) | KDM4EMAPK1TSHRSLC6A4 | |
| SCHEMBL6751558 | 0.73 | SIGMAR1 (0.36) | — | |
| SCHEMBL6749853 | 0.72 | KDM1A (0.46) | ALDH1A1SMN1; SMN2MAPK1HTR1A | |
| SCHEMBL6751559 | 0.70 | MC4R (0.44) | ALDH1A1LMNATSHR | |
| SCHEMBL6744792 | 0.67 | TK1 (0.40) | — | |
| SCHEMBL812683 | 0.66 | ALDH1A1 (0.75) | ALDH1A1KDM4ELMNAPKMSMN1; SMN2 | |
| SCHEMBL7094855 | 0.65 | L3MBTL1 (0.59) | ALDH1A1LMNAMAPK1MBTD1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-11100373-A | — | — | None | — | — | JP | disclosed |
| JP-H11100373-A | NEW PHENOTHIAZINE DERIVATIVE AND ITS MEDICINE | EISAI CO LTD | 1999-04-13 | — | — | JP | disclosed |