Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OXTR | P30559 | 2/20 | 0.44 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | NR1D1 | P20393 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | BCL2 | P10415 | 1/20 | 0.38 |
| ▸ | BAD | Q92934 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8342472 | 0.87 | LMNA (0.42) | OXTRAVPR1AMEN1KMT2APOLB | |
| SCHEMBL4419743 | 0.86 | OXTR (0.45) | OXTRAVPR1AMEN1KMT2APOLB | |
| SCHEMBL302021 | 0.86 | OXTR (0.45) | OXTRAVPR1AMEN1KMT2APOLB | |
| SCHEMBL4419739 | 0.86 | OXTR (0.45) | OXTRAVPR1AMEN1KMT2APOLB | |
| SCHEMBL13709449 | 0.86 | NR1D1 (0.39) | OXTRAVPR1AMEN1KMT2APOLB | |
| SCHEMBL8342892 | 0.85 | OXTR (0.50) | OXTRAVPR1AMEN1KMT2APOLB | |
| SCHEMBL8341237 | 0.84 | HPGD (0.42) | OXTRAVPR1AMEN1KMT2APOLB | |
| SCHEMBL8343791 | 0.82 | OXTR (0.37) | OXTRAVPR1AMEN1KMT2APOLB | |
| SCHEMBL8338121 | 0.82 | HPGD (0.41) | OXTRAVPR1AMEN1KMT2APOLB | |
| SCHEMBL4419146 | 0.82 | OXTR (0.66) | OXTRAVPR1AMEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1532109-B1 | PYRROLIDINE DERIVATIVES AS OXYTOCIN ANTAGONISTS | MERCK SERONO SA (CH) | 2009-09-09 | — | — | EP | disclosed |
| WO-2004005249-A1 | PYRROLIDINE DERIVATIVES AS OXYTOCIN ANTAGONISTS | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2004-01-15 | — | — | WO | disclosed |