Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | OXTR | P30559 | 2/20 | 0.39 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.39 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | FASN | P49327 | 1/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | BDKRB2 | P30411 | 1/20 | 0.37 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8342892 | 0.88 | OXTR (0.50) | HPGDMAPK1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL8338121 | 0.86 | HPGD (0.41) | HPGDMAPK1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL4418365 | 0.85 | HPGD (0.43) | HPGDMAPK1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL4418361 | 0.85 | HPGD (0.43) | HPGDMAPK1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL8343604 | 0.84 | OXTR (0.44) | HPGDMAPK1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL8344306 | 0.82 | OXTR (0.41) | HPGDMAPK1SMN1; SMN2POLBOXTR | |
| SCHEMBL13709449 | 0.82 | NR1D1 (0.39) | HPGDMAPK1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL8341197 | 0.82 | HPGD (0.47) | HPGDMAPK1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL8342472 | 0.81 | LMNA (0.42) | HPGDMAPK1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL13709427 | 0.81 | MMP2 (0.43) | HPGDMAPK1SMN1; SMN2POLBOXTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1532109-B1 | PYRROLIDINE DERIVATIVES AS OXYTOCIN ANTAGONISTS | MERCK SERONO SA (CH) | 2009-09-09 | — | — | EP | disclosed |
| WO-2004005249-A1 | PYRROLIDINE DERIVATIVES AS OXYTOCIN ANTAGONISTS | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2004-01-15 | — | — | WO | disclosed |