SCHEMBL8346148

SCHEMBL8346148

Cc1ccc(CNCc2ccccn2)cc1

nearest known ligand 0.55

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 4/20 0.55
ALDH1A1 P00352 2/20 0.55
CHRM2 P08172 1/20 0.53
NPSR1 Q6W5P4 1/20 0.51
NPC1 O15118 1/20 0.51
RAB9A P51151 1/20 0.51
SMN1; SMN2 Q16637 1/20 0.51
CYP3A4 P08684 1/20 0.50
MEN1 O00255 1/20 0.50
KMT2A Q03164 1/20 0.50
MAPT P10636 1/20 0.50
CXCR4 P61073 1/20 0.49
ALOX15 P16050 1/20 0.49
SCN8A Q9UQD0 1/20 0.49
TP53 P04637 1/20 0.48
HPGD P15428 1/20 0.48
KDM4E B2RXH2 1/20 0.48
MAOA P21397 1/20 0.47
MAOB P27338 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29466164 1.00 L3MBTL1 (0.55) L3MBTL1ALDH1A1CHRM2NPSR1NPC1
Ammonia Solution, Strong SCHEMBL3313079 0.98 L3MBTL1 (0.54) L3MBTL1ALDH1A1CHRM2NPSR1NPC1
SCHEMBL29860055 0.91 L3MBTL1 (0.62) L3MBTL1ALDH1A1CHRM2SMN1; SMN2MEN1
SCHEMBL3314110 0.91 L3MBTL1 (0.62) L3MBTL1ALDH1A1CHRM2SMN1; SMN2MEN1
SCHEMBL12963429 0.86 RAB9A (0.57) L3MBTL1ALDH1A1CHRM2NPSR1NPC1
SCHEMBL2947235 0.85 ALDH1A1 (0.63) L3MBTL1ALDH1A1CHRM2SMN1; SMN2MEN1
SCHEMBL2854302 0.85 CYP1A2 (0.56) L3MBTL1ALDH1A1CHRM2NPSR1ALOX15
SCHEMBL29438821 0.83 CHRM2 (0.70) L3MBTL1ALDH1A1CHRM2SMN1; SMN2MEN1
SCHEMBL230222 0.83 CHRM2 (0.70) L3MBTL1ALDH1A1CHRM2SMN1; SMN2MEN1
SCHEMBL3906840 0.83 ALDH1A1 (0.55) L3MBTL1ALDH1A1CHRM2SMN1; SMN2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113512039-B Cu detection based on complexation+Fluorescent probe and application thereof 广东石油化工学院 2022-03-29 CN claimed
CN-113512039-A Cu detection based on complexation+Fluorescent probe and application thereof 广东石油化工学院 2021-10-19 CN claimed
US-20250136594-A1 COMPOUNDS AND METHODS OF USE TANGO THERAPEUTICS, INC. 2025-05-01 US disclosed
EP-4469438-A1 COMPOUNDS AND METHODS OF USE Tango Therapeutics, Inc. (US) 2024-12-04 EP disclosed
WO-2023146987-A1 COMPOUNDS AND METHODS OF USE TANGO THERAPEUTICS, INC. (US) 2023-08-03 WO disclosed
WO-2023146987-A1 COMPOUNDS AND METHODS OF USE TANGO THERAPEUTICS, INC. (US) 2023-08-03 WO disclosed
CN-113512039-B Cu detection based on complexation+Fluorescent probe and application thereof 广东石油化工学院 2022-03-29 CN disclosed
CN-113512039-A Cu detection based on complexation+Fluorescent probe and application thereof 广东石油化工学院 2021-10-19 CN disclosed
WO-2004069823-A1 INHIBITORS OF HISTONE DEACETYLASE METHYLGENE, INC. (CA) 2004-08-19 WO disclosed
WO-2003024448-A2 INHIBITORS OF HISTONE DEACETYLASE METHYLGENE, INC. (CA) 2003-03-27 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250136594-A1 COMPOUNDS AND METHODS OF USE CNKSR1, UGT1A1, REV1 L3MBTL1 4699/4885ALDH1A1 29/4885CHRM2 1738/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.