Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 8/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 8/20 | 1.00 |
| ▸ | RECQL | P46063 | 4/20 | 1.00 |
| ▸ | STK17B | O94768 | 3/20 | 1.00 |
| ▸ | MAOA | P21397 | 3/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 1.00 |
| ▸ | NPC1 | O15118 | 2/20 | 1.00 |
| ▸ | GAA | P10253 | 2/20 | 1.00 |
| ▸ | MAPT | P10636 | 2/20 | 1.00 |
| ▸ | AURKA | O14965 | 2/20 | 1.00 |
| ▸ | GSK3B | P49841 | 2/20 | 1.00 |
| ▸ | CDK5 | Q00535 | 2/20 | 1.00 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 1.00 |
| ▸ | PSMD14 | O00487 | 1/20 | 1.00 |
| ▸ | DAPK3 | O43293 | 1/20 | 1.00 |
| ▸ | JAK2 | O60674 | 1/20 | 1.00 |
| ▸ | ALPL | P05186 | 1/20 | 1.00 |
| ▸ | ALPI | P09923 | 1/20 | 1.00 |
| ▸ | ALPG | P10696 | 1/20 | 1.00 |
| ▸ | CDK4 | P11802 | 1/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuretin SCHEMBL30214394 | 1.00 | MEN1 (1.00) | MEN1KMT2ARECQLSTK17BMAOA | |
| Sulfuretin SCHEMBL30214408 | 1.00 | MEN1 (1.00) | MEN1KMT2ARECQLSTK17BMAOA | |
| Sulfuretin SCHEMBL634007 | 1.00 | MEN1 (1.00) | MEN1KMT2ARECQLSTK17BMAOA | |
| Sulfuretin SCHEMBL634006 | 1.00 | MEN1 (1.00) | MEN1KMT2ARECQLSTK17BMAOA | |
| Sulfuretin SCHEMBL29545005 | 1.00 | MEN1 (1.00) | MEN1KMT2ARECQLSTK17BMAOA | |
| SCHEMBL30337058 | 0.89 | STK17B (1.00) | MEN1KMT2ARECQLSTK17BMAOA | |
| SCHEMBL5707753 | 0.88 | TYR (1.00) | MEN1KMT2ARECQLSTK17BMAOA | |
| SCHEMBL29435856 | 0.88 | TYR (1.00) | MEN1KMT2ARECQLSTK17BMAOA | |
| SCHEMBL30214422 | 0.88 | TYR (1.00) | MEN1KMT2ARECQLSTK17BMAOA | |
| SCHEMBL6964950 | 0.88 | MEN1 (0.78) | MEN1KMT2ARECQLSTK17BMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7524836-B2 | Nitrooxyderivative steroidal compounds | NICOX S.A. (FR) | 2009-04-28 | — | — | US | disclosed |
| US-7378412-B2 | Pharmaceutical compounds | NICOX S.A. (FR) | 2008-05-27 | — | — | US | disclosed |
| US-7378412-B2 | Pharmaceutical compounds | NICOX S.A. (FR) | 2008-05-27 | — | — | US | disclosed |
| US-20070142342-A1 | Pharmaceutical compounds | NICOX S.A. | 2007-06-21 | — | — | US | disclosed |
| US-20070142342-A1 | Pharmaceutical compounds | NICOX S.A. | 2007-06-21 | — | — | US | disclosed |
| US-7186708-B2 | Steroidal compounds | NICOX S.A. (FR) | 2007-03-06 | — | — | US | disclosed |
| US-7186708-B2 | Steroidal compounds | NICOX S.A. (FR) | 2007-03-06 | — | — | US | disclosed |
| US-20070010458-A1 | Drugs for the arthritis treatment | NICOX S.A. (FR) | 2007-01-11 | — | — | US | disclosed |
| US-20070010458-A1 | Drugs for the arthritis treatment | NICOX S.A. (FR) | 2007-01-11 | — | — | US | disclosed |
| WO-2003095471-A2 | DEOXYCHOLIC ACID DERIVATIVES FOR THE TREATMENT OF ACUTE DYSFUNCTIONS OF PORTAL AND HEPATIC VENOUS CIRCULATION | NICOX S.A. (IT) | 2003-11-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070142342-A1 | Pharmaceutical compounds | CYP11B2, CYP11B1, CYP2S1 | MEN1 533/4885KMT2A 4240/4885RECQL 488/4885 |
| US-20070010458-A1 | Drugs for the arthritis treatment | PTGS1, ADORA2B, PTGS2 | MEN1 3932/4885KMT2A 4003/4885RECQL 901/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.