Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR2 | P50052 | 2/20 | 0.61 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | TLR7 | Q9NYK1 | 15/20 | 0.45 |
| ▸ | TLR8 | Q9NR97 | 3/20 | 0.44 |
| ▸ | PDE4A | P27815 | 1/20 | 0.44 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.44 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9028849 | 0.88 | KMT2A (0.66) | AGTR2AGTR1KMT2ATLR7PDE4A | |
| SCHEMBL29109918 | 0.86 | AGTR1 (0.59) | AGTR2AGTR1KMT2ATLR7TLR8 | |
| SCHEMBL9043935 | 0.84 | KMT2A (0.65) | AGTR2AGTR1KMT2ATLR7PDE4A | |
| SCHEMBL9028574 | 0.80 | KMT2A (0.62) | AGTR2AGTR1KMT2ATLR7PDE4A | |
| SCHEMBL9029790 | 0.75 | KMT2A (0.61) | AGTR2AGTR1KMT2ATLR7 | |
| SCHEMBL9424026 | 0.74 | PDE4A (0.46) | AGTR2AGTR1TLR7PDE4APDE4B | |
| SCHEMBL8568897 | 0.71 | AGTR1 (0.59) | AGTR2AGTR1 | |
| SCHEMBL8346282 | 0.70 | AGTR2 (0.51) | AGTR2AGTR1 | |
| SCHEMBL8350558 | 0.68 | AGTR1 (0.48) | AGTR2AGTR1TLR7TLR8 | |
| SCHEMBL15703662 | 0.68 | TLR7 (0.54) | AGTR2AGTR1TLR7TLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6005105-A | Process for producing imidazole derivative | PHARMACIA & UPJOHN COMPANY (US) | 1999-12-21 | — | — | US | disclosed |
| EP-0705266-B1 | PROCESS FOR PRODUCING IMIDAZOLE DERIVATIVE | UPJOHN CO (US) | 1997-02-26 | — | — | EP | disclosed |