Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 2/20 | 0.42 |
| ▸ | ENPP2 | Q13822 | 6/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | SLC6A9 | P48067 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8343038 | 0.92 | TBXA2R (0.42) | TBXA2RENPP2LMNARXFP1ALDH1A1 | |
| SCHEMBL8344845 | 0.90 | PKM (0.41) | TBXA2RENPP2LMNARXFP1GRIN1 | |
| SCHEMBL6968454 | 0.90 | ENPP2 (0.39) | TBXA2RENPP2LMNAGRIN1GRIN2B | |
| SCHEMBL6967782 | 0.90 | LMNA (0.39) | TBXA2RENPP2LMNARXFP1TP53 | |
| SCHEMBL8347165 | 0.90 | LMNA (0.45) | TBXA2RENPP2LMNARXFP1MEN1 | |
| SCHEMBL6975612 | 0.89 | GRIN1 (0.35) | ENPP2LMNAGRIN1GRIN2BTP53 | |
| SCHEMBL7085890 | 0.87 | GSK3B (0.34) | ENPP2LMNAGRIN1GRIN2BTP53 | |
| SCHEMBL6975055 | 0.87 | GRIN1 (0.35) | ENPP2LMNAGRIN1GRIN2BTP53 | |
| SCHEMBL6975545 | 0.87 | GRIN1 (0.34) | ENPP2LMNAGRIN1GRIN2BTP53 | |
| SCHEMBL8345427 | 0.87 | TBXA2R (0.37) | TBXA2RSLC6A9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5910506-A | IMIDAZOLE DERIVATIVES, E.G.5-(3,5-DICHLOROPHENYLTHIO)-1,2-DIMETHYL-4-ISOPROPYL-1H-IMIDAZOLE; VIRICIDES; AIDS; NONTOXIC | SHIONOGI & CO., LTD. (JP) | 1999-06-08 | — | — | US | disclosed |