Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | ENPP2 | Q13822 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.38 |
| ▸ | TBXAS1 | P24557 | 7/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6973501 | 0.93 | LMNA (0.40) | PKMENPP2LMNAHDAC6TBXA2R | |
| SCHEMBL6969581 | 0.91 | ENPP2 (0.37) | PKMENPP2LMNAGRIN1GRIN2B | |
| SCHEMBL8347170 | 0.90 | TBXA2R (0.42) | ENPP2LMNATBXA2RGRIN1GRIN2B | |
| SCHEMBL8342977 | 0.90 | LMNA (0.45) | ENPP2LMNAHDAC6TBXAS1PTGDR2 | |
| SCHEMBL8345861 | 0.90 | LMNA (0.42) | ENPP2LMNAHDAC6TBXA2RGRIN1 | |
| SCHEMBL6975548 | 0.89 | GRIN1 (0.38) | ENPP2TBXA2RGRIN1GRIN2B | |
| SCHEMBL6969811 | 0.88 | GRIN1 (0.37) | ENPP2TBXA2RGRIN1GRIN2B | |
| SCHEMBL6972991 | 0.88 | GRIN1 (0.38) | GRIN1GRIN2B | |
| SCHEMBL7083464 | 0.87 | GRIN1 (0.39) | LMNAGRIN1GRIN2BKDM4EALDH1A1 | |
| SCHEMBL7080841 | 0.87 | GRIN1 (0.36) | ENPP2LMNAGRIN1GRIN2BPTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5910506-A | IMIDAZOLE DERIVATIVES, E.G.5-(3,5-DICHLOROPHENYLTHIO)-1,2-DIMETHYL-4-ISOPROPYL-1H-IMIDAZOLE; VIRICIDES; AIDS; NONTOXIC | SHIONOGI & CO., LTD. (JP) | 1999-06-08 | — | — | US | disclosed |