Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VNN1 | O95497 | 1/20 | 0.32 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.32 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.31 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.31 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8351974 | 0.88 | PDCD1 (0.34) | PDCD1CD274ADORA2AADORA1 | |
| SCHEMBL8346826 | 0.75 | ADORA2A (0.32) | PIK3CAADORA2AADORA1 | |
| SCHEMBL8346831 | 0.74 | SIRT6 (0.31) | — | |
| SCHEMBL8351344 | 0.74 | KDM4E (0.36) | PDCD1CD274ADORA2AADORA1 | |
| SCHEMBL8349224 | 0.71 | EED (0.30) | — | |
| SCHEMBL8942458 | 0.69 | ALDH1A1 (0.38) | — | |
| SCHEMBL8349375 | 0.68 | LMNA (0.33) | — | |
| SCHEMBL21639278 | 0.66 | ITGB3 (0.45) | — | |
| SCHEMBL21639276 | 0.66 | ITGB3 (0.45) | — | |
| SCHEMBL8346430 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5958904-A | Phosphonomethyl-imidazo 1,2-A! pyrimidine-2-carboxylic acid compounds for treatment of neurotoxic injury | G.D. SEARLE & CO. (US) | 1999-09-28 | — | — | US | disclosed |