Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.32 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.32 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.32 |
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.31 |
| ▸ | FABP3 | P05413 | 1/20 | 0.31 |
| ▸ | FABP4 | P15090 | 1/20 | 0.31 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | HSP90B1 | P14625 | 2/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 2/20 | 0.30 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6965470 | 0.81 | SETDB1 (0.33) | SMN1; SMN2HSP90B1USP7HSP90AA1HSP90AB1 | |
| SCHEMBL7087407 | 0.78 | RECQL (0.30) | RECQLUSP7 | |
| SCHEMBL6975988 | 0.78 | DRD2 (0.31) | FABP3FABP4FABP5HSP90B1 | |
| SCHEMBL6165069 | 0.77 | RECQL (0.30) | RECQL | |
| SCHEMBL6968462 | 0.76 | — | — | |
| SCHEMBL6966628 | 0.76 | DRD2 (0.34) | HSP90B1RECQLHSP90AA1HSP90AB1TRAP1 | |
| SCHEMBL6960253 | 0.76 | PTGDR2 (0.32) | FABP3FABP4FABP5HSP90B1USP7 | |
| SCHEMBL8345289 | 0.76 | DRD2 (0.32) | HSP90B1HSP90AA1HSP90AB1TRAP1 | |
| SCHEMBL8345413 | 0.75 | ALDH1A1 (0.35) | SMN1; SMN2GAAMEN1KMT2AHSP90B1 | |
| SCHEMBL6973791 | 0.75 | CYP2C9 (0.33) | HSP90B1RECQLHSP90AA1HSP90AB1TRAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5910506-A | IMIDAZOLE DERIVATIVES, E.G.5-(3,5-DICHLOROPHENYLTHIO)-1,2-DIMETHYL-4-ISOPROPYL-1H-IMIDAZOLE; VIRICIDES; AIDS; NONTOXIC | SHIONOGI & CO., LTD. (JP) | 1999-06-08 | — | — | US | disclosed |