Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1B | P49286 | 5/20 | 0.53 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.43 |
| ▸ | HTR1A | P08908 | 7/20 | 0.42 |
| ▸ | HTR1D | P28221 | 5/20 | 0.42 |
| ▸ | HTR1B | P28222 | 5/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 2/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | DRD1 | P21728 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27529224 | 0.76 | MTNR1B (0.61) | MTNR1BHTR1AHTR1DHTR1BKDM4E | |
| SCHEMBL8347285 | 0.76 | MTNR1B (0.61) | MTNR1BHTR1AHTR1DHTR1BKDM4E | |
| SCHEMBL8349457 | 0.75 | MTNR1B (0.52) | MTNR1BMTNR1AHTR1AHTR1DHTR1B | |
| SCHEMBL8344536 | 0.73 | MTNR1B (0.62) | MTNR1BMTNR1AHTR1AHTR1DHTR1B | |
| SCHEMBL8344546 | 0.73 | SIGMAR1 (0.53) | MTNR1BHTR1AHTR1DHTR1BKDM4E | |
| SCHEMBL8343954 | 0.70 | SIGMAR1 (0.58) | MTNR1BHTR1AHTR1DHTR1BKDM4E | |
| SCHEMBL6000211 | 0.69 | HTR1A (0.75) | MTNR1BHTR1AHTR1DHTR1BKDM4E | |
| SCHEMBL8349189 | 0.69 | MTNR1B (0.46) | MTNR1BHTR1AHTR1DHTR1BHTR2C | |
| SCHEMBL8344543 | 0.69 | MTNR1B (0.43) | MTNR1BMTNR1AHTR1AHTR1DHTR1B | |
| SCHEMBL8344544 | 0.68 | MTNR1B (0.43) | MTNR1BMTNR1AHTR1AHTR1DHTR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5929078-A | ANTISEROTONINE AGENT | SYNTHELABO (FR) | 1999-07-27 | — | — | US | disclosed |