Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.47 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.47 |
| ▸ | HTR2C | P28335 | 2/20 | 0.46 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.43 |
| ▸ | GALR1 | P47211 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | XDH | P47989 | 1/20 | 0.43 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.42 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | RXRA | P19793 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | PGR | P06401 | 1/20 | 0.40 |
| ▸ | KIF11 | P52732 | 1/20 | 0.40 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8352439 | 0.80 | TDP2 (0.45) | NOTUMGALR1PDCD1CD274PARP1 | |
| SCHEMBL1065756 | 0.74 | HTR2C (0.53) | PARP10PARP11HTR2CNOTUMASIC3 | |
| SCHEMBL8347265 | 0.74 | AXL (0.42) | PARP10PARP11NOTUMMAPT | |
| SCHEMBL11218334 | 0.72 | NOTUM (0.45) | PARP10PARP11NOTUMASIC3MAPT | |
| SCHEMBL8349987 | 0.71 | ASIC3 (0.64) | PARP10PARP11HTR2CMEN1KMT2A | |
| SCHEMBL29678302 | 0.71 | TSHR (0.58) | HTR2CNOTUMASIC3IDO1PGR | |
| SCHEMBL1263144 | 0.71 | TSHR (0.58) | HTR2CNOTUMASIC3IDO1PGR | |
| SCHEMBL2532289 | 0.71 | HTR2C (0.50) | PARP10PARP11HTR2CNOTUMASIC3 | |
| SCHEMBL8689815 | 0.70 | HTR2C (0.62) | PARP10PARP11HTR2CMEN1KMT2A | |
| SCHEMBL3897160 | 0.70 | SRD5A2 (0.62) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5861416-A | TREATMENT OF ASTHMA OR COUGH | MERRELL PHARMACEUTICALS INC. (US) | 1999-01-19 | — | — | US | disclosed |
| US-5824690-A | TREATING ASTHMA, COUGH | HOECHST MARION ROUSSEL INC. (US) | 1998-10-20 | — | — | US | disclosed |