Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 4/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA3 | P07451 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | CA6 | P23280 | 1/20 | 0.33 |
| ▸ | CA5A | P35218 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28351910 | 1.00 | BRD4 (0.38) | BRD4CA1CA2TSHRLMNA | |
| SCHEMBL20225963 | 1.00 | BRD4 (0.38) | BRD4CA1CA2TSHRLMNA | |
| SCHEMBL13596600 | 1.00 | BRD4 (0.38) | BRD4CA1CA2TSHRLMNA | |
| SCHEMBL14282520 | 1.00 | BRD4 (0.38) | BRD4CA1CA2TSHRLMNA | |
| SCHEMBL4409953 | 1.00 | BRD4 (0.38) | BRD4CA1CA2TSHRLMNA | |
| SCHEMBL29809272 | 1.00 | BRD4 (0.38) | BRD4CA1CA2TSHRLMNA | |
| SCHEMBL8352237 | 0.89 | BRD4 (0.36) | BRD4CA1CA2TSHRLMNA | |
| SCHEMBL30885557 | 0.86 | ALDH1A1 (0.38) | BRD4CA1CA2TSHRLMNA | |
| SCHEMBL14048425 | 0.86 | LMNA (0.35) | BRD4CA1CA2TSHRLMNA | |
| SCHEMBL8350327 | 0.86 | BRD4 (0.38) | BRD4CA1CA2TSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114634437-B | Simple preparation method of brivaracetam | 武汉氟本氘合新材料科技有限公司 | 2023-05-30 | — | — | CN | claimed |
| CN-111170881-B | Preparation method of buvaracetam intermediate | 上海医药集团股份有限公司 | 2023-08-01 | — | — | CN | disclosed |
| US-11673862-B2 | Processes to produce brivaracetam | SUZHOU PENGXU PHARMATECH CO. LTD. (CN) | 2023-06-13 | — | — | US | disclosed |
| CN-114634437-B | Simple preparation method of brivaracetam | 武汉氟本氘合新材料科技有限公司 | 2023-05-30 | — | — | CN | disclosed |
| CN-115557873-A | Synthesis method of methyl esterification impurity of brivaracetam | 浙江美诺华药物化学有限公司 | 2023-01-03 | — | — | CN | disclosed |
| CN-114634437-A | Simple preparation method of brivaracetam | 武汉氟本氘合新材料科技有限公司 | 2022-06-17 | — | — | CN | disclosed |
| CN-113234004-A | Novel preparation process of brivaracetam | 河北唯达生物医药产业技术研究有限公司 | 2021-08-10 | — | — | CN | disclosed |
| WO-2020051796-A1 | PREPARATION METHOD FOR BRIVARACETAM AND INTERMEDIATE THEREOF | 上海宣泰医药科技有限公司 | 2020-03-19 | — | — | WO | disclosed |
| WO-2020052545-A1 | METHOD FOR PREPARING BRIVARACETAM AND INTERMEDIATES THEREOF | 上海宣泰医药科技有限公司 | 2020-03-19 | — | — | WO | disclosed |
| CN-108503573-B | A kind of new preparation method of Bu Waxitan | 北京艾百诺医药股份有限公司 | 2019-11-22 | — | — | CN | disclosed |
| CN-108689903-A | A kind of new preparation method of Bu Waxitan | 北京艾百诺医药股份有限公司 | 2018-10-23 | — | — | CN | disclosed |
| CN-108503573-A | A kind of new preparation method of Bu Waxitan | 北京艾百诺医药股份有限公司 | 2018-09-07 | — | — | CN | disclosed |
| US-7563912-B2 | Oxopyrrolidine compounds, preparation of said compounds and their use in the manufacturing of Levetiracetam and analogues | UCB PHARMA, S.A. (BE) | 2009-07-21 | — | — | US | disclosed |
| US-7563912-B2 | Oxopyrrolidine compounds, preparation of said compounds and their use in the manufacturing of Levetiracetam and analogues | UCB PHARMA, S.A. (BE) | 2009-07-21 | — | — | US | disclosed |
| US-20070142647-A1 | Oxopyrrolidine compounds, preparation of said compounds and their use in the manufacturing of levetiracetam and analogues | ATES CELAL | 2007-06-21 | — | — | US | disclosed |
| US-20070142647-A1 | Oxopyrrolidine compounds, preparation of said compounds and their use in the manufacturing of levetiracetam and analogues | ATES CELAL | 2007-06-21 | — | — | US | disclosed |
| WO-2003014080-A2 | OXOPYRROLIDINE COMPOUNDS, PREPARATION OF SAID COMPOUNDS AND THEIR USE IN THE MANUFACTURING OF LEVETIRACETAM AND ANALOGUES | UCB, S.A. (BE) | 2003-02-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11673862-B2 | Processes to produce brivaracetam | BLVRB, CYP3A4, POR | BRD4 157/4885CA1 4013/4885CA2 2398/4885 |
| US-20070142647-A1 | Oxopyrrolidine compounds, preparation of said compounds and their use in the manufacturing of levetiracetam and analogues | CYP2D6, OTC, CYP2B6 | BRD4 1778/4885CA1 1400/4885CA2 1347/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.