Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 4/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA3 | P07451 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | CA6 | P23280 | 1/20 | 0.33 |
| ▸ | CA5A | P35218 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28351910 | 1.00 | BRD4 (0.38) | BRD4CA1CA2TSHRLMNA | |
| SCHEMBL20225963 | 1.00 | BRD4 (0.38) | BRD4CA1CA2TSHRLMNA | |
| SCHEMBL13596600 | 1.00 | BRD4 (0.38) | BRD4CA1CA2TSHRLMNA | |
| SCHEMBL8350417 | 1.00 | BRD4 (0.38) | BRD4CA1CA2TSHRLMNA | |
| SCHEMBL14282520 | 1.00 | BRD4 (0.38) | BRD4CA1CA2TSHRLMNA | |
| SCHEMBL4409953 | 1.00 | BRD4 (0.38) | BRD4CA1CA2TSHRLMNA | |
| SCHEMBL8352237 | 0.89 | BRD4 (0.36) | BRD4CA1CA2TSHRLMNA | |
| SCHEMBL30885557 | 0.86 | ALDH1A1 (0.38) | BRD4CA1CA2TSHRLMNA | |
| SCHEMBL14048425 | 0.86 | LMNA (0.35) | BRD4CA1CA2TSHRLMNA | |
| SCHEMBL8350327 | 0.86 | BRD4 (0.38) | BRD4CA1CA2TSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4036244-B1 | ENZYMATIC PROCESS FOR THE PREPARATION OF (2S)-2-[(4R)-2-OXO-4-PROPYL-PYRROLIDIN-1-YL]BUTYRIC ACID AND ITS CONVERSION INTO BRIVARACETAM | DIVIS LABORATORIES LTD (IN) | 2023-10-11 | — | — | EP | disclosed |
| JP-2022117945-A | ENZYMATIC PROCESS FOR PREPARATION OF (2S)-2-[(4R)-2-OXO-4-PROPYL-PYRROLIDIN-1-YL]BUTYRIC ACID AND CONVERSION TO BRIVARACETAM THEREOF | ディヴィズ・ラボラトリーズ・リミテッド | 2022-08-12 | — | — | JP | disclosed |
| US-20220241242-A1 | ENZYMATIC PROCESS FOR THE PREPARATION OF (2S)-2-[(4R)-2-OXO-4-PROPYL-PYRROLIDIN-1-YL]BUTYRIC ACID AND ITS CONVERSION INTO BRIVARACETAM | DIVIS LABORATORIES LTD (IN) | 2022-08-04 | — | — | US | disclosed |
| US-20220241242-A1 | ENZYMATIC PROCESS FOR THE PREPARATION OF (2S)-2-[(4R)-2-OXO-4-PROPYL-PYRROLIDIN-1-YL]BUTYRIC ACID AND ITS CONVERSION INTO BRIVARACETAM | DIVIS LABORATORIES LTD (IN) | 2022-08-04 | — | — | US | disclosed |
| US-11400074-B1 | Enzymatic process for the preparation of (2S)-2-[(4R)-2-oxo-4-propyl-pyrrolidin-1-yl]butyric acid and its conversion into brivaracetam | DIVI'S LABORATORIES LTD. (IN) | 2022-08-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11400074-B1 | Enzymatic process for the preparation of (2S)-2-[(4R)-2-oxo-4-propyl-pyrrolidin-1-yl]butyric acid and its conversion into brivaracetam | BPGM, GABRP, GABRB1 | BRD4 72/4885CA1 355/4885CA2 167/4885 |
| US-20220241242-A1 | ENZYMATIC PROCESS FOR THE PREPARATION OF (2S)-2-[(4R)-2-OXO-4-PROPYL-PYRROLIDIN-1-YL]BUTYRIC ACID AND ITS CONVERSION INTO BRIVARACETAM | BPGM, GABRP, GABRB1 | BRD4 73/4885CA1 365/4885CA2 162/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.