Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 3/20 | 0.43 |
| ▸ | HTR7 | P34969 | 2/20 | 0.43 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.43 |
| ▸ | HTR3B | O95264 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | NCF1 | P14598 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | HTR1D | P28221 | 1/20 | 0.43 |
| ▸ | HTR1B | P28222 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | MTOR | P42345 | 1/20 | 0.43 |
| ▸ | HTR3A | P46098 | 1/20 | 0.43 |
| ▸ | HTR5A | P47898 | 1/20 | 0.43 |
| ▸ | HTR6 | P50406 | 1/20 | 0.43 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.43 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8344543 | 0.88 | MTNR1B (0.43) | HTR1AHTR7CYP1A2HTR1DHTR1B | |
| SCHEMBL8343949 | 0.81 | MTNR1B (0.44) | HTR1AHTR7CYP1A2HTR1DHTR1B | |
| SCHEMBL8346145 | 0.77 | HTR1A (0.43) | HTR1AHTR7HTR3EHTR3BCYP1A2 | |
| SCHEMBL4244450 | 0.72 | HTR6 (0.61) | HTR1AHTR7HTR3EHTR3BCYP1A2 | |
| SCHEMBL4247868 | 0.72 | HTR6 (0.61) | HTR1AHTR7HTR3EHTR3BCYP1A2 | |
| SCHEMBL4244446 | 0.72 | HTR6 (0.61) | HTR1AHTR7HTR3EHTR3BCYP1A2 | |
| Hydrochloric Acid SCHEMBL8336358 | 0.69 | ADRB1 (0.38) | HTR1AHTR7HTR1DHTR2AHTR3A | |
| SCHEMBL4241274 | 0.68 | HTR6 (0.55) | HTR1AHTR7HTR3EHTR3BCYP1A2 | |
| SCHEMBL4241279 | 0.68 | HTR6 (0.55) | HTR1AHTR7HTR3EHTR3BCYP1A2 | |
| SCHEMBL8344544 | 0.68 | MTNR1B (0.43) | HTR1AHTR7HTR1DHTR1BHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5929078-A | ANTISEROTONINE AGENT | SYNTHELABO (FR) | 1999-07-27 | — | — | US | disclosed |