SCHEMBL8350993

SCHEMBL8350993

CCN(C)c1ccc(C(C)=O)cc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.54
KMT2A Q03164 2/20 0.54
POLB P06746 2/20 0.54
GAA P10253 2/20 0.54
MEN1 O00255 1/20 0.54
MCL1 Q07820 1/20 0.54
NOX1 Q9Y5S8 1/20 0.54
RAB9A P51151 3/20 0.52
NPC1 O15118 2/20 0.52
KDM4E B2RXH2 1/20 0.52
MAPK1 P28482 1/20 0.52
ADRA2A P08913 1/20 0.47
ADRA2B P18089 1/20 0.47
ADRA2C P18825 1/20 0.47
HPGD P15428 3/20 0.43
LMNA P02545 2/20 0.43
L3MBTL1 Q9Y468 2/20 0.43
ALDH1A1 P00352 1/20 0.43
PYCR1 P32322 1/20 0.43
SMN1; SMN2 Q16637 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18806570 0.89 MAPT (0.70) MAPTKMT2APOLBGAAMEN1
SCHEMBL15722856 0.85 RAB9A (0.53) MAPTKMT2APOLBGAAMEN1
SCHEMBL82487 0.85 HPGD (0.61) MAPTKMT2APOLBGAAMEN1
SCHEMBL13639055 0.83 MAPT (0.47) MAPTKMT2APOLBGAAMEN1
SCHEMBL1784560 0.83 ALDH1A1 (0.52) MAPTKMT2APOLBMEN1RAB9A
SCHEMBL11800833 0.83 ADRA2A (0.47) MAPTKMT2APOLBGAAMEN1
SCHEMBL23247969 0.82 ADRA2A (0.46) MAPTKMT2APOLBGAAMEN1
SCHEMBL27525040 0.82 ADRA2A (0.46) MAPTKMT2APOLBGAAMEN1
SCHEMBL13331926 0.82 ADRA2A (0.55) MAPTKMT2APOLBMAPK1ADRA2A
SCHEMBL181431 0.81 MAPT (0.77) MAPTKMT2APOLBGAAMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3604365-B1 CONJUGATED DIENE POLYMER AND METHOD FOR PRODUCING CONJUGATED DIENE POLYMER SUMITOMO CHEMICAL CO (JP) 2024-04-24 EP disclosed
CN-113748134-B Conjugated diene copolymer and method for producing conjugated diene copolymer 瑞住合成橡胶株式会社 2024-03-08 CN disclosed
CN-110461893-B Conjugated diene polymer and method for producing conjugated diene polymer 住友化学株式会社 2023-10-27 CN disclosed
EP-3495394-B1 METHOD FOR PRODUCING MODIFIED CONJUGATED DIENE POLYMER AND METHOD FOR PRODUCING POLYMER COMPOSITION SUMITOMO CHEMICAL CO (JP) 2023-04-12 EP disclosed
US-11377513-B2 Conjugated diene polymer and method for producing conjugated diene polymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2022-07-05 US disclosed
US-20220185919-A1 CONJUGATED DIENE COPOLYMER AND METHOD FOR MANUFACTURING CONJUGATED DIENE COPOLYMER ZS ELASTOMERS CO., LTD. (JP) 2022-06-16 US disclosed
CN-109563186-B Method for producing modified conjugated diene polymer and method for producing polymer composition 住友化学株式会社 2022-04-15 CN disclosed
EP-3950724-A1 CONJUGATED DIENE COPOLYMER AND METHOD FOR MANUFACTURING CONJUGATED DIENE COPOLYMER ZS Elastomers Co., Ltd. (JP) 2022-02-09 EP disclosed
US-11174282-B2 Aminosteroid derivatives and process for producing same UNIVERSITé LAVAL (CA) 2021-11-16 US disclosed
US-11046791-B2 Method for producing modified conjugated diene polymer and method for producing polymer composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2021-06-29 US disclosed
US-20140088242-A1 METHOD FOR PRODUCING MODIFIED CONJUGATED DIENE-BASED POLYMER, AND METHOD FOR PRODUCING POLYMER COMPOSITION ZEON CORPORATION (JP) 2014-03-27 US disclosed
US-8304556-B2 Thiazolyl-dihydro-indazoles BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2012-11-06 US disclosed
CN-102731722-A Process for producing modified conjugated diene-based polymer, modified conjugated diene-based polymer, and polymer composition SUMITOMO CHEMICAL CO 2012-10-17 CN disclosed
US-20120252966-A1 PROCESS FOR PRODUCING MODIFIED CONJUGATED DIENE-BASED POLYMER, MODIFIED CONJUGATED DIENE-BASED POLYMER, AND POLYMER COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED 2012-10-04 US disclosed
US-20120245275-A1 PROCESS FOR PRODUCING CONJUGATED DIENE-BASED POLYMER, CONJUGATED DIENE-BASED POLYMER, AND CONJUGATED DIENE-BASED POLYMER COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED 2012-09-27 US disclosed
US-20120190771-A1 PROCESS FOR PRODUCING CONJUGATED DIENE-BASED POLYMER, CONJUGATED DIENE-BASED POLYMER, AND CONJUGATED DIENE-BASED POLYMER COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED 2012-07-26 US disclosed
US-20120190770-A1 PROCESS FOR PRODUCING CONJUGATED DIENE-BASED POLYMER, CONJUGATED DIENE-BASED POLYMER, AND CONJUGATED DIENE-BASED POLYMER COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED 2012-07-26 US disclosed
US-20120108567-A1 Thiazolyl-Dihydro-Indazoles BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2012-05-03 US disclosed
US-20110118208-A1 Thiazolyl-Dihydro-Indazoles BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2011-05-19 US disclosed
WO-2004007501-A1 BIOLOGICALLY ACTIVE COMPOUNDS AMURA THERAPEUTICS LIMITED (GB) 2004-01-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120108567-A1 Thiazolyl-Dihydro-Indazoles MKI67, CYP11B1, IGF1R MAPT 2509/4885KMT2A 2863/4885POLB 3933/4885
US-20110118208-A1 Thiazolyl-Dihydro-Indazoles MKI67, CYP11B1, IGF1R MAPT 2509/4885KMT2A 2863/4885POLB 3933/4885
US-11174282-B2 Aminosteroid derivatives and process for producing same HSD17B11, HSD17B7, CYP19A1 MAPT 3922/4885KMT2A 3255/4885POLB 2608/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.