Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.47 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.47 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | RXRA | P19793 | 3/20 | 0.45 |
| ▸ | RXRB | P28702 | 3/20 | 0.45 |
| ▸ | RXRG | P48443 | 2/20 | 0.45 |
| ▸ | HCAR3 | P49019 | 3/20 | 0.45 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.44 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18821758 | 0.89 | NPC1 (0.70) | ALDH1A1NPC1MEN1POLBKMT2A | |
| SCHEMBL15722856 | 0.85 | RAB9A (0.53) | ALDH1A1NPC1MEN1POLBKMT2A | |
| SCHEMBL82487 | 0.85 | HPGD (0.61) | ALDH1A1NPC1MEN1POLBKMT2A | |
| SCHEMBL11146761 | 0.84 | HCAR3 (0.58) | ALDH1A1NPC1MEN1POLBKMT2A | |
| SCHEMBL11800833 | 0.83 | ADRA2A (0.47) | ALDH1A1NPC1MEN1POLBKMT2A | |
| Butane SCHEMBL2586584 | 0.83 | NPC1 (0.67) | ALDH1A1NPC1MEN1POLBKMT2A | |
| SCHEMBL8350993 | 0.83 | MAPT (0.54) | ALDH1A1NPC1MEN1POLBKMT2A | |
| SCHEMBL8633955 | 0.82 | HPGD (0.67) | ALDH1A1NPC1MEN1KMT2AADRA2A | |
| SCHEMBL23247969 | 0.82 | ADRA2A (0.46) | ALDH1A1NPC1MEN1POLBKMT2A | |
| SCHEMBL13331926 | 0.82 | ADRA2A (0.55) | ALDH1A1POLBKMT2ATSHRADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4314302-A1 | TETRACYCLINE-INDUCIBLE EXPRESSION SYSTEMS | DNA TWOPOINTO INC. (US) | 2024-02-07 | — | — | EP | disclosed |
| US-20230323396-A1 | TETRACYCLINE-INDUCIBLE EXPRESSION SYSTEM | DNA TWOPOINTO INC. (US) | 2023-10-12 | — | — | US | disclosed |
| US-11566262-B2 | Tetracycline-inducible expression systems | DNA TWOPOINTO INC. (US) | 2023-01-31 | — | — | US | disclosed |
| US-10071027-B2 | Dental composites | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2018-09-11 | — | — | US | disclosed |
| US-20170087062-A1 | DENTAL COMPOSITES | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2017-03-30 | — | — | US | disclosed |
| US-20170014419-A1 | MEDICAMENT FOR SUPPRESSING MALIGNANT TUMOR METASTASIS | NATIONAL CEREBRAL AND CARDIOVASCULAR CENTER (JP) | 2017-01-19 | — | — | US | disclosed |
| EP-1797186-B1 | EXPRESSION SYSTEM, COMPONENTS THEREOF AND METHODS OF USE | NAT RES COUNCIL CANADA (CA) | 2016-05-25 | — | — | EP | disclosed |
| WO-2015142886-A1 | DENTAL COMPOSITES | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2015-09-24 | — | — | WO | disclosed |
| US-8728759-B2 | Reverse cumate repressor mutant | NATIONAL RESEARCH COUNCIL OF CANADA (CA) | 2014-05-20 | — | — | US | disclosed |
| US-8476430-B2 | Fused heterocyclic compounds useful as kinase modulators | BRISTOL-MYERS SQUIBB COMPANY (US) | 2013-07-02 | — | — | US | disclosed |
| US-20080311618-A1 | Expression System, Components Thereof and Methods of Use | NATIONAL RESEARCH COUNCIL OF CANADA (CA) | 2008-12-18 | — | — | US | disclosed |
| EP-1797186-A4 | EXPRESSION SYSTEM, COMPONENTS THEREOF AND METHODS OF USE | CA NAT RESEARCH COUNCIL (CA) | 2008-11-12 | — | — | EP | disclosed |
| EP-1797186-A1 | EXPRESSION SYSTEM, COMPONENTS THEREOF AND METHODS OF USE | NATIONAL RESEARCH COUNCIL OF CANADA (CA) | 2007-06-20 | — | — | EP | disclosed |
| WO-2006037215-A1 | EXPRESSION SYSTEM, COMPONENTS THEREOF AND METHODS OF USE | NATIONAL RESEARCH COUNCIL OF CANADA (CA) | 2006-04-13 | — | — | WO | disclosed |
| WO-2006000085-A1 | HEPATITIS C INHIBITOR PEPTIDE ANALOGS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2006-01-05 | — | — | WO | disclosed |
| US-20040205834-A1 | System for inducible expression in eukaryotic cells | NATIONAL RESEARCH COUNCIL OF CANADA (CA) | 2004-10-14 | — | — | US | disclosed |
| EP-1385946-A2 | A SYSTEM FOR INDUCIBLE EXPRESSION IN EUKARYOTIC CELLS | NATIONAL RESEARCH COUNCIL OF CANADA (CA) | 2004-02-04 | — | — | EP | disclosed |
| WO-2002088346-A2 | A SYSTEM FOR INDUCIBLE EXPRESSION IN EUKARYOTIC CELLS | NATIONAL RESEARCH COUNCIL OF CANADA (CA) | 2002-11-07 | — | — | WO | disclosed |
| US-4011173-A | MODIFIED NEMATIC MIXTURES WITH POSITIVE DIELECTRIC ANISOTROPY | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) | 1977-03-08 | — | — | US | disclosed |
| US-3936462-A | CNS DEPRESSANT, ANALGESIC | STERLING DRUG INC. (US) | 1976-02-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170087062-A1 | DENTAL COMPOSITES | TERT, ITGA8, TTPA | ALDH1A1 182/4885NPC1 4257/4885MEN1 4331/4885 |
| US-20170014419-A1 | MEDICAMENT FOR SUPPRESSING MALIGNANT TUMOR METASTASIS | AGTR2, MME, AGTR1 | ALDH1A1 2036/4885NPC1 2415/4885MEN1 725/4885 |
| US-10071027-B2 | Dental composites | TERT, ITGA8, TTPA | ALDH1A1 182/4885NPC1 4257/4885MEN1 4331/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.