SCHEMBL8352020

SCHEMBL8352020

CC(C)CCNCCCN

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 5/20 0.57
CA6 P23280 5/20 0.57
CA7 P43166 5/20 0.57
CA9 Q16790 5/20 0.57
CA14 Q9ULX7 5/20 0.57
CA5B Q9Y2D0 5/20 0.57
CA2 P00918 4/20 0.57
CA4 P22748 4/20 0.57
CA5A P35218 4/20 0.57
ALOX15 P16050 3/20 0.57
CASP2 P42575 2/20 0.57
F13A1 P00488 2/20 0.57
CYP1A2 P05177 2/20 0.57
THPO P40225 2/20 0.57
MEN1 O00255 2/20 0.57
RECQL P46063 2/20 0.57
KMT2A Q03164 2/20 0.57
CYP2C19 P33261 1/20 0.57
HSD17B10 Q99714 1/20 0.57
CA3 P07451 3/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18158019 0.98 CA12 (0.55) CA12CA6CA7CA9CA14
Hydrochloric Acid SCHEMBL11553303 0.98 UBE2N (0.59) CA12CA6CA7CA9CA14
SCHEMBL12335786 0.93 CA12 (0.59) CA12CA6CA7CA9CA14
SCHEMBL21799750 0.91 CA12 (0.56) CA12CA6CA7CA9CA14
SCHEMBL21799439 0.91 CA12 (0.56) CA12CA6CA7CA9CA14
SCHEMBL21799994 0.91 CA12 (0.56) CA12CA6CA7CA9CA14
SCHEMBL21799567 0.91 CA12 (0.56) CA12CA6CA7CA9CA14
SCHEMBL21799730 0.91 CA12 (0.56) CA12CA6CA7CA9CA14
SCHEMBL21799615 0.91 CA12 (0.56) CA12CA6CA7CA9CA14
SCHEMBL18232511 0.91 CA12 (0.56) CA12CA6CA7CA9CA14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3623398-B1 RESIN COMPOSITION COMPRISING A MODIFIED BLOCK COPOLYMER AND METHOD FOR PRODUCING MODIFIED BLOCK COPOLYMER ASAHI CHEMICAL IND (JP) 2024-08-28 EP disclosed
US-11697804-B2 Transcriptionally targeted and CpG-free plasmid for theranostic gene therapy THE JOHNS HOPKINS UNIVERSITY (US) 2023-07-11 US disclosed
US-20230002790-A1 POLY(Beta-AMINO ESTER) NANOPARTICLES FOR THE NON-VIRAL DELIVERY OF PLASMID DNA FOR GENE EDITING AND RETINAL GENE THERAPY THE JOHNS HOPKINS UNIVERSITY 2023-01-05 US disclosed
CN-110603273-B Modified block copolymer, method for producing modified block copolymer, and resin composition 旭化成株式会社 2022-10-14 CN disclosed
US-20220154219-A1 GENE DELIVERY PARTICLES TO INDUCE TUMOR-DERIVED ANTIGEN PRESENTING CELLS THE JOHNS HOPKINS UNIVERSITY 2022-05-19 US disclosed
US-11124593-B2 Modified block copolymer, method for producing modified block copolymer, and resin composition ASAHI KASEI KABUSHIKI KAISHA (JP) 2021-09-21 US disclosed
US-20200330396-A1 NONVIRAL GENE TRANSFER TO THE SUPRACHOROIDAL SPACE THE JOHNS HOPKINS UNIVERSITY 2020-10-22 US disclosed
US-20200199282-A1 Modified Block Copolymer, Method for Producing Modified Block Copolymer, and Resin Composition ASAHI KASEI KABUSHIKI KAISHA (JP) 2020-06-25 US disclosed
US-20200140831-A1 TRANSCRIPTIONALLY TARGETED AND CPG-FREE PLASMID FOR THERANOSTIC GENE THERAPY THE JOHNS HOPKINS UNIVERSITY 2020-05-07 US disclosed
EP-3623398-A1 MODIFIED BLOCK COPOLYMER, METHOD FOR PRODUCING MODIFIED BLOCK COPOLYMER, AND RESIN COMPOSITION Asahi Kasei Kabushiki Kaisha (JP) 2020-03-18 EP disclosed
CN-110603273-A Modified block copolymer, method for producing modified block copolymer, and resin composition 旭化成株式会社 2019-12-20 CN disclosed
EP-3293195-A1 COMPOUNDS FOR USE IN TREATING DIABETES OHR Pharmaceutical, Inc. (US) 2018-03-14 EP disclosed
CN-107074734-A Process for making N-alkyl polyamines 库扎环球有限责任公司 2017-08-18 CN disclosed
WO-2010022076-A1 TRIAZOLOPYRIDINE COMPOUNDS AS PIM KINASE INHIBITORS ARRAY BIOPHARMA INC. (US) 2010-02-25 WO disclosed
US-7371733-B2 Anti bacterial compounds UTAH STATE UNIVERSITY (US) 2008-05-13 US disclosed
WO-2003101382-A2 COMPOUNDS USEFUL IN THE TREATMENT OF ANTHRAX AND INHIBITING LETHAL FACTOR MERCK & CO., INC. (US) 2003-12-11 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200330396-A1 NONVIRAL GENE TRANSFER TO THE SUPRACHOROIDAL SPACE MYOC, MTREX, SLC26A4 CA12 704/4885CA6 422/4885CA7 1440/4885
US-20220154219-A1 GENE DELIVERY PARTICLES TO INDUCE TUMOR-DERIVED ANTIGEN PRESENTING CELLS PBK, MICA, STAT3 CA12 3289/4885CA6 3564/4885CA7 4222/4885
US-11697804-B2 Transcriptionally targeted and CpG-free plasmid for theranostic gene therapy POLRMT, HDGF, PCNP CA12 1062/4885CA6 1100/4885CA7 1694/4885
US-20200140831-A1 TRANSCRIPTIONALLY TARGETED AND CPG-FREE PLASMID FOR THERANOSTIC GENE THERAPY POLRMT, HDGF, PCNP CA12 1062/4885CA6 1100/4885CA7 1694/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.