SCHEMBL8352111

SCHEMBL8352111

CCCCC(CC=O)CCC

nearest known ligand 0.43

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TSHR P16473 6/20 0.43
ALDH1A1 P00352 3/20 0.43
CYP3A4 P08684 3/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
TDP1 Q9NUW8 2/20 0.39
CA2 P00918 2/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
LMNA P02545 1/20 0.34
FAAH O00519 2/20 0.33
TRPV1 Q8NER1 1/20 0.33
CTSK P43235 1/20 0.33
ADH1B P00325 1/20 0.33
ADH1C P00326 1/20 0.33
ADH1A P07327 1/20 0.33
ADH4 P08319 1/20 0.33
ADH7 P40394 1/20 0.33
FDPS P14324 1/20 0.33
DNM1 Q05193 1/20 0.33
ATM Q13315 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3099299 0.95 TSHR (0.46) TSHRALDH1A1CYP3A4SMN1; SMN2TDP1
SCHEMBL276625 0.93 LMNA (0.43) TSHRALDH1A1CYP3A4SMN1; SMN2LMNA
SCHEMBL9263689 0.91 LMNA (0.46) TSHRLMNAFAAHTRPV1ADH1B
SCHEMBL2961306 0.91 LMNA (0.46) TSHRLMNAFAAHTRPV1ADH1B
SCHEMBL3850489 0.91 LMNA (0.46) TSHRLMNAFAAHTRPV1ADH1B
SCHEMBL3841827 0.91 LMNA (0.46) TSHRLMNAFAAHTRPV1ADH1B
SCHEMBL3847166 0.91 LMNA (0.46) TSHRLMNAFAAHTRPV1ADH1B
SCHEMBL7733731 0.91 LMNA (0.46) TSHRLMNAFAAHTRPV1ADH1B
SCHEMBL11030873 0.90 TSHR (0.46) TSHRALDH1A1CYP3A4SMN1; SMN2TDP1
SCHEMBL3844336 0.90 ALDH1A1 (0.38) TSHRALDH1A1CYP3A4SMN1; SMN2TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5831135-A CATALYST SELECTIVITY; PURITY HUELS AKTIENGESELLSCHAFT (DE) 1998-11-03 US claimed
US-5675045-A Process for the catalytic selective hydrogenation of polyunsaturated organic substances HUELS AKTIENGESELLSCHAFT (DE) 1997-10-07 US claimed
EP-0753496-A2 Process for the catalytic selective hydrogenation of multiple unsaturated organic substances HÜLS AKTIENGESELLSCHAFT (DE) 1997-01-15 EP claimed
US-20230406801-A1 PROCESSES TO IMPROVE CATALYTIC METAL ACCOUNTABILITY IN HYDROFORMYLATION PROCESSES DOW TECHNOLOGY INVESTMENTS LLC (US) 2023-12-21 US disclosed
EP-4259598-A1 PROCESSES TO IMPROVE CATALYTIC METAL ACCOUNTABILITY IN HYDROFORMYLATION PROCESSES Dow Technology Investments LLC (US) 2023-10-18 EP disclosed
CN-116635362-A Method for improving the metering of catalytic metals in hydroformylation processes 陶氏技术投资有限责任公司 2023-08-22 CN disclosed
WO-2022132372-A1 PROCESSES TO IMPROVE CATALYTIC METAL ACCOUNTABILITY IN HYDROFORMYLATION PROCESSES DOW TECHNOLOGY INVESTMENTS LLC (US) 2022-06-23 WO disclosed
WO-2017048956-A1 NUCLEOTIDE ANALOGS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2017-03-23 WO disclosed
US-5998635-A CATALYTIC CYCLIZATION AN ALDEHYDE WITH A KETENE TAKASAGO INTERNATIONAL CORPORATION (JP) 1999-12-07 US disclosed
US-5831135-A CATALYST SELECTIVITY; PURITY HUELS AKTIENGESELLSCHAFT (DE) 1998-11-03 US disclosed
US-5675045-A Process for the catalytic selective hydrogenation of polyunsaturated organic substances HUELS AKTIENGESELLSCHAFT (DE) 1997-10-07 US disclosed
EP-0753496-A2 Process for the catalytic selective hydrogenation of multiple unsaturated organic substances HÜLS AKTIENGESELLSCHAFT (DE) 1997-01-15 EP disclosed
US-5072057-A Isomeric alcohol mixture for producing plasticizers and surfac tants EXXON RESEARCH & ENGINEERING CO. (US) 1991-12-10 US disclosed
US-5030774-A Reacting petroleum distillates with carbon monoxide and hydrogen to form aldehyde in presence of carbonyl compounds hydrogenation to form alcohols EXXON RESEARCH AND ENGINEERING CO. (US) 1991-07-09 US disclosed
EP-0329670-A1 A PROCESS FOR THE HYDROFORMYLATION OF SULFUR-CONTAINING THERMALLY CRACKED PETROLEUM RESIDUA AND NOVEL PRODUCTS THEREOF. EXXON RESEARCH ENGINEERING CO (US) 1989-08-30 EP disclosed
EP-0329670-A4 A PROCESS FOR THE HYDROFORMYLATION OF SULFUR-CONTAINING THERMALLY CRACKED PETROLEUM RESIDUA AND NOVEL PRODUCTS THEREOF. EXXON RESEARCH ENGINEERING CO (US) 1989-08-16 EP disclosed
WO-1988002360-A1 A PROCESS FOR THE HYDROFORMYLATION OF SULFUR-CONTAINING THERMALLY CRACKED PETROLEUM RESIDUA AND NOVEL PRODUCTS THEREOF EXXON RESEARCH AND ENGINEERING COMPANY (US) 1988-04-07 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230406801-A1 PROCESSES TO IMPROVE CATALYTIC METAL ACCOUNTABILITY IN HYDROFORMYLATION PROCESSES RTF1, PYM1, CYP4F11 TSHR 2999/4885ALDH1A1 2462/4885CYP3A4 1107/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.