Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 17/20 | 0.55 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8354405 | 0.93 | PLA2G2A (0.65) | PLA2G2APLA2G1BMEN1POLBKMT2A | |
| SCHEMBL8356918 | 0.91 | PLA2G2A (0.51) | PLA2G2APLA2G1B | |
| SCHEMBL8356407 | 0.89 | PLA2G2A (0.51) | PLA2G2AMEN1KMT2ATP53GAA | |
| SCHEMBL8360160 | 0.87 | PTGS2 (0.40) | PLA2G2A | |
| SCHEMBL8356964 | 0.84 | PLA2G2A (0.50) | PLA2G2APLA2G1B | |
| SCHEMBL8359033 | 0.84 | LMNA (0.49) | PLA2G2A | |
| SCHEMBL8356646 | 0.84 | PTGS2 (0.49) | PLA2G2A | |
| SCHEMBL8356293 | 0.83 | PLA2G2A (0.61) | PLA2G2APLA2G1BMEN1KMT2A | |
| SCHEMBL8355151 | 0.83 | PLA2G2A (0.53) | PLA2G2APLA2G1B | |
| SCHEMBL8356721 | 0.81 | PLA2G2A (0.39) | PLA2G2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5877202-A | Indole derivatives useful to treat estrogen-related neoplasms and disorders | AVENTISUB II INC. | 1999-03-02 | — | — | US | claimed |
| US-5877202-A | Indole derivatives useful to treat estrogen-related neoplasms and disorders | AVENTISUB II INC. | 1999-03-02 | — | — | US | disclosed |