Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.65 |
| ▸ | ADORA1 | P30542 | 6/20 | 0.65 |
| ▸ | ADORA2A | P29274 | 5/20 | 0.63 |
| ▸ | ADORA2B | P29275 | 4/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.59 |
| ▸ | PNP | P00491 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | GMNN | O75496 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8576753 | 0.87 | ADORA1 (0.60) | ADORA3ADORA1ADORA2AADORA2BKMT2A | |
| SCHEMBL8575318 | 0.81 | ADORA1 (0.65) | ADORA3ADORA1ADORA2AADORA2BKMT2A | |
| SCHEMBL5229239 | 0.80 | ADORA3 (0.61) | ADORA3ADORA1ADORA2AADORA2BKMT2A | |
| SCHEMBL8358871 | 0.80 | ADORA3 (0.94) | ADORA3ADORA1ADORA2AADORA2BKMT2A | |
| SCHEMBL9170264 | 0.79 | ADORA1 (0.62) | ADORA3ADORA1ADORA2AADORA2BKMT2A | |
| SCHEMBL8355407 | 0.79 | ADORA3 (1.00) | ADORA3ADORA1ADORA2AADORA2BKMT2A | |
| SCHEMBL8118476 | 0.79 | ADORA1 (1.00) | ADORA3ADORA1ADORA2AADORA2BKMT2A | |
| SCHEMBL8020381 | 0.78 | ADORA2B (0.68) | ADORA3ADORA1ADORA2AADORA2BKMT2A | |
| SCHEMBL8579784 | 0.78 | ADORA1 (0.65) | ADORA3ADORA1ADORA2AADORA2BKMT2A | |
| SCHEMBL5229734 | 0.78 | ADORA2B (1.00) | ADORA3ADORA1ADORA2AADORA2BKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999031101-A1 | ADENOSINE RECEPTOR ANTAGONISTS WITH IMPROVED BIOACTIVITY | UNIVERSITY OF SOUTH FLORIDA (US) | 1999-06-24 | — | — | WO | disclosed |