SCHEMBL8355247

SCHEMBL8355247

COC(=O)C(F)(Cl)C(=O)CF

nearest known ligand 0.34

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.34
MAPT P10636 1/20 0.34
DGAT1 O75907 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9806073 0.81 DGAT1 (0.39) ALDH1A1MAPTDGAT1
SCHEMBL8165932 0.79 ALDH1A1 (0.36) ALDH1A1MAPT
SCHEMBL197338 0.77 ALDH1A1 (0.33) ALDH1A1MAPTDGAT1
SCHEMBL8153782 0.75
SCHEMBL8691770 0.72 ALDH1A1 (0.38) ALDH1A1
SCHEMBL3592898 0.71
SCHEMBL132957 0.71
SCHEMBL23869987 0.69
SCHEMBL19675764 0.68
SCHEMBL5861742 0.68

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240410055-A1 METHOD AND FORMULATION FOR PREPARING OPTICAL METAL OXIDE LAYERS MERCK PATENT GMBH (DE) 2024-12-12 US disclosed
WO-2023057401-A1 METHOD AND FORMULATION FOR PREPARING OPTICAL METAL OXIDE LAYERS MERCK PATENT GMBH (DE) 2023-04-13 WO disclosed
US-5877119-A HERBICIDE ROHM AND HAAS COMPANY (US) 1999-03-02 US disclosed
US-5843867-A Substituted pyridine compounds ROHM AND HAAS COMPANY (US) 1998-12-01 US disclosed
US-5824625-A HERBICIDES, HETEROCYCLIC GROUP(S) ATTACHED TO PYRIDINE RING ROHM AND HAAS COMPANY 1998-10-20 US disclosed
US-5643854-A HERBICIDES ROHM AND HAAS COMPANY (US) 1997-07-01 US disclosed
US-5512536-A HERBICIDE ROHN AND HAAS COMPANY (US) 1996-04-30 US disclosed
US-5424274-A Herbicides ROHM AND HAAS COMPANY (US) 1995-06-13 US disclosed
US-5391540-A Herbicides ROHM AND HAAS COMPANY (US) 1995-02-21 US disclosed
EP-0435843-B1 Substituted pyridine compounds MONSANTO CO (US) 1994-06-15 EP disclosed
US-5219824-A Preemergence, postemergence herbicides MONSANTO COMPANY (US) 1993-06-15 US disclosed
EP-0278944-B1 SUBSTITUTED 2,6-SUBSTITUTED PYRIDINE COMPOUNDS Monsanto Company (US) 1992-09-30 EP disclosed
WO-1992014711-A1 SUBSTITUTED PYRIDINE COMPOUNDS MONSANTO COMPANY (US) 1992-09-03 WO disclosed
US-5129943-A Herbicides MONSANTO COMPANY (US) 1992-07-14 US disclosed
US-5125956-A Preemergence herbicides MONSANTO COMPANY (US) 1992-06-30 US disclosed
US-5100461-A Substituted 2,6-substituted pyridine compounds having herbicidal activity MONSANTO COMPANY (US) 1992-03-31 US disclosed
US-4988384-A HERBICIDES, PLANT GROWTH REGULATORS, ANTIGROWTH AGENTS MONSANTO COMPANY (US) 1991-01-29 US disclosed
US-4826532-A HERBICIDES MONSANTO COMPANY (US) 1989-05-02 US disclosed
EP-0278945-A2 Substituted 2,6-substituted pyridine compounds Monsanto Company (US) 1988-08-17 EP disclosed
EP-0278944-A1 Substituted 2,6-substituted pyridine compounds Monsanto Company (US) 1988-08-17 EP disclosed