SCHEMBL8355293

SCHEMBL8355293

O=S(=O)(Nc1c2ccccc2cc2ccccc12)c1ccccc1

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
G6PD P11413 1/20 0.66
RECQL P46063 1/20 0.59
FFAR4 Q5NUL3 1/20 0.56
LMNA P02545 2/20 0.54
SMN1; SMN2 Q16637 2/20 0.54
CYTH2 Q99418 1/20 0.53
TSHR P16473 1/20 0.53
HKDC1 Q2TB90 1/20 0.53
IL1RN P18510 1/20 0.52
KEAP1 Q14145 1/20 0.52
ERAP1 Q9NZ08 1/20 0.52
ALDH1A1 P00352 4/20 0.51
KMT2A Q03164 3/20 0.51
MEN1 O00255 2/20 0.51
MAPT P10636 1/20 0.51
METAP2 P50579 1/20 0.50
METAP1 P53582 1/20 0.50
HSD17B2 P37059 1/20 0.49
PKM P14618 1/20 0.48
SLC40A1 Q9NP59 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3259256 0.80 G6PD (1.00) G6PDRECQLLMNASMN1; SMN2CYTH2
SCHEMBL7577515 0.75 SMN1; SMN2 (0.65) G6PDRECQLLMNASMN1; SMN2TSHR
SCHEMBL1428546 0.74 RECQL (1.00) G6PDRECQLLMNASMN1; SMN2KEAP1
SCHEMBL16743633 0.73 G6PD (0.37) G6PDRECQLLMNAHKDC1KEAP1
SCHEMBL14703301 0.73 CA2 (0.44) G6PD
SCHEMBL9577140 0.73 NR3C1 (0.44) G6PDALDH1A1KMT2AMEN1PKM
SCHEMBL9577179 0.73 CCR4 (0.54) SLC40A1
SCHEMBL4955668 0.72 KEAP1 (0.59) FFAR4SMN1; SMN2CYTH2TSHRIL1RN
SCHEMBL812686 0.72 FFAR4 (1.00) FFAR4SMN1; SMN2CYTH2KMT2AMEN1
SCHEMBL25749441 0.72 FFAR4 (0.68) FFAR4CYTH2TSHRIL1RNKEAP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1999041756-A1 INTRINSICALLY CONDUCTIVE POLYMER BLENDS HAVING A LOW PERCOLATION THRESHOLD ZIPPERLING KESSLER & CO. (GMBH & CO.) (DE) 1999-08-19 WO disclosed
US-5908898-A ELECTRICALLY INSULATIVE THERMOPLASTIC MATRIX POLYMER DISPERSED THROUGH AN INTRINSICALLY CONDUCTIVE POLYMER SALT THAT IS INCOMPATIBLE WITH THE MATRIX POLYMER, A THERMOPLASTIC CONDUCTIVE PHASE POLYMER THAT IS PARTIALLY COMPATIBLE WITH MONSANTO COMPANY (US) 1999-06-01 US disclosed
WO-1999019391-A1 INTRINSICALLY CONDUCTIVE POLYMER/PLASTICIZER BLENDS WITH ENHANCED CONDUCTIVITY ZIPPERLING KESSLER & CO. (GMBH & CO.) (DE) 1999-04-22 WO disclosed
US-5871671-A Intrinsically conductive polymer/plasticizer blends with enhanced conductivity MONSANTO COMPANY (US) 1999-02-16 US disclosed