Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 1/20 | 0.44 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.43 |
| ▸ | CCR4 | P51679 | 2/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.42 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | PTGES2 | Q9H7Z7 | 3/20 | 0.40 |
| ▸ | WDR5 | P61964 | 2/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.40 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | FABP4 | P15090 | 1/20 | 0.39 |
| ▸ | G6PD | P11413 | 1/20 | 0.38 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9577179 | 0.88 | CCR4 (0.54) | HCRTR1CCR4PTGES2SLC40A1 | |
| SCHEMBL9577124 | 0.77 | SMN1; SMN2 (0.56) | PFKFB3MEN1KMT2APKMSLC22A12 | |
| SCHEMBL9577186 | 0.74 | PGR (0.57) | PFKFB3MEN1KMT2AALDH1A1PTGES2 | |
| SCHEMBL8355293 | 0.73 | G6PD (0.66) | MEN1KMT2AALDH1A1SLC40A1PKM | |
| SCHEMBL6766698 | 0.70 | PKM (0.45) | NR3C1CCR4PFKFB3ALDH1A1PTGES2 | |
| SCHEMBL2055425 | 0.68 | G6PD (0.51) | HCRTR1SLC40A1G6PD | |
| SCHEMBL2157528 | 0.67 | PFKFB3 (0.52) | PFKFB3MEN1KMT2APTGES2WDR5 | |
| Naphthalene SCHEMBL11663266 | 0.66 | CYP2A6 (0.39) | NR3C1PFKFB3CYP2A6PKM | |
| SCHEMBL9577092 | 0.66 | NR3C1 (0.50) | NR3C1CCR4PFKFB3ALDH1A1WDR5 | |
| SCHEMBL14018756 | 0.66 | ALDH1A1 (0.68) | PFKFB3MEN1KMT2AALDH1A1WDR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5264474-A | Plasticizing thermoplastic or thermosetting resins with sulfonamide compounds | MTM AMERICAS INC. (US) | 1993-11-23 | — | — | US | disclosed |
| US-4957957-A | Polymer compositions containing aromatic sulfonamide | ETHYL CORPORATION (US) | 1990-09-18 | — | — | US | disclosed |