Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | PLAU | P00749 | 2/20 | 0.40 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.36 |
| ▸ | GRM5 | P41594 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.34 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8384228 | 0.89 | PLAU (0.49) | LMNAPLAUALDH1A1HTTNPC1 | |
| SCHEMBL8355716 | 0.83 | LMNA (0.44) | LMNAPLAU | |
| SCHEMBL8355557 | 0.82 | PLAU (0.46) | LMNAPLAUL3MBTL1 | |
| SCHEMBL8351885 | 0.81 | ALDH1A1 (0.45) | LMNAPLAUALDH1A1L3MBTL1 | |
| SCHEMBL10958740 | 0.80 | L3MBTL1 (0.42) | LMNAGRM5ALDH1A1MEN1HTT | |
| SCHEMBL8355749 | 0.80 | HTR3A (0.42) | LMNAPLAUMEN1KMT2A | |
| SCHEMBL8356051 | 0.80 | LMNA (0.38) | LMNAPLAU | |
| SCHEMBL11089115 | 0.78 | ALDH1A1 (0.36) | LMNAGRM5ALDH1A1MEN1KMT2A | |
| SCHEMBL11083931 | 0.78 | BCHE (0.39) | LMNAGRM5MEN1KMT2A | |
| SCHEMBL11083937 | 0.78 | BCHE (0.39) | LMNAGRM5MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5952361-A | Compositions | DIAS NAHOUM CESAR ROBERTO (US) | 1999-09-14 | — | — | US | disclosed |
| US-5908853-A | THERAPY FOR SEXUAL DISORDERS | Nahoum, Cesar Roberto Dias (BR) | 1999-06-01 | — | — | US | disclosed |
| US-5773457-A | Compositions | Nahoum, Cesar Roberto Dias (BR) | 1998-06-30 | — | — | US | disclosed |