Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | NOS3 | P29474 | 1/20 | 0.34 |
| ▸ | NOS1 | P29475 | 1/20 | 0.34 |
| ▸ | NOS2 | P35228 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8355672 | 0.89 | LMNA (0.44) | PLAULMNARAB9AL3MBTL1NPC1 | |
| SCHEMBL11158296 | 0.88 | PLAU (0.43) | PLAULMNARAB9AL3MBTL1TDP1 | |
| SCHEMBL11096324 | 0.87 | PLAU (0.42) | PLAURAB9AL3MBTL1TDP1NPC1 | |
| Hydrochloric Acid SCHEMBL11217448 | 0.86 | PLAU (0.41) | PLAULMNARAB9AL3MBTL1TDP1 | |
| SCHEMBL8355557 | 0.84 | PLAU (0.46) | PLAULMNAL3MBTL1ADORA2AMAPT | |
| SCHEMBL11181834 | 0.84 | HRH2 (0.40) | PLAULMNAADORA2AMAPT | |
| Hydrochloric Acid SCHEMBL11191536 | 0.83 | HRH2 (0.40) | PLAULMNAADORA2AMAPT | |
| SCHEMBL11096144 | 0.83 | HTR1A (0.39) | PLAULMNARAB9AL3MBTL1ADORA2A | |
| SCHEMBL8351885 | 0.83 | ALDH1A1 (0.45) | PLAULMNAL3MBTL1ALDH1A1HSD17B10 | |
| SCHEMBL8355716 | 0.82 | LMNA (0.44) | PLAULMNATDP1NOS3NOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5908853-A | THERAPY FOR SEXUAL DISORDERS | Nahoum, Cesar Roberto Dias (BR) | 1999-06-01 | — | — | US | disclosed |
| US-5773457-A | Compositions | Nahoum, Cesar Roberto Dias (BR) | 1998-06-30 | — | — | US | disclosed |