Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP8 | P22894 | 8/20 | 0.57 |
| ▸ | MMP2 | P08253 | 8/20 | 0.57 |
| ▸ | MMP9 | P14780 | 6/20 | 0.57 |
| ▸ | MMP1 | P03956 | 4/20 | 0.55 |
| ▸ | MMP3 | P08254 | 1/20 | 0.55 |
| ▸ | ACE | P12821 | 2/20 | 0.53 |
| ▸ | ECE1 | P42892 | 2/20 | 0.53 |
| ▸ | MMP7 | P09237 | 1/20 | 0.52 |
| ▸ | GHSR | Q92847 | 1/20 | 0.52 |
| ▸ | NPY1R | P25929 | 2/20 | 0.50 |
| ▸ | NPY2R | P49146 | 2/20 | 0.50 |
| ▸ | NPY4R | P50391 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8354772 | 0.99 | MMP2 (0.59) | MMP8MMP2MMP9MMP1MMP3 | |
| SCHEMBL8358360 | 0.99 | MMP2 (0.59) | MMP8MMP2MMP9MMP1MMP3 | |
| SCHEMBL8357061 | 0.92 | ACE (0.60) | MMP8MMP2MMP9MMP1MMP3 | |
| SCHEMBL17253329 | 0.87 | MMP8 (0.57) | MMP8MMP2MMP9MMP1MMP3 | |
| SCHEMBL8357063 | 0.87 | MMP8 (0.53) | MMP8MMP2MMP9MMP1MMP3 | |
| SCHEMBL8354508 | 0.87 | MMP8 (0.53) | MMP8MMP2MMP9MMP1MMP3 | |
| SCHEMBL21929719 | 0.84 | MMP9 (0.64) | MMP8MMP2MMP9MMP1MMP3 | |
| SCHEMBL20845644 | 0.84 | MMP8 (0.51) | MMP8MMP2MMP9MMP1MMP3 | |
| SCHEMBL8357553 | 0.84 | ACE (0.72) | MMP8MMP2MMP9ACEECE1 | |
| SCHEMBL92821 | 0.83 | MMP2 (0.54) | MMP8MMP2MMP9MMP1MMP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003017924-A2 | LIPOPEPTIDE STEREOISOMERS, METHODS FOR PREPARING SAME, AND USEFUL INTERMEDIATES | CUBIST PHARMACEUTICALS, INC. (US) | 2003-03-06 | — | — | WO | disclosed |