Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 4/20 | 0.54 |
| ▸ | MMP8 | P22894 | 4/20 | 0.54 |
| ▸ | MMP1 | P03956 | 2/20 | 0.54 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.52 |
| ▸ | IL23R | Q5VWK5 | 1/20 | 0.50 |
| ▸ | CCKBR | P32239 | 4/20 | 0.49 |
| ▸ | CCKAR | P32238 | 1/20 | 0.49 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.49 |
| ▸ | MMP9 | P14780 | 2/20 | 0.49 |
| ▸ | KISS1R | Q969F8 | 9/20 | 0.49 |
| ▸ | MAGI3 | Q5TCQ9 | 1/20 | 0.48 |
| ▸ | MMP7 | P09237 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10157514 | 0.91 | CCKBR (0.54) | ERBB2IL23RCCKBRCCKAROPRD1 | |
| SCHEMBL8357061 | 0.85 | ACE (0.60) | MMP2MMP8MMP1MMP9MMP7 | |
| SCHEMBL8227196 | 0.84 | CCKAR (0.56) | ERBB2CCKBRCCKAROPRD1KISS1R | |
| SCHEMBL8354772 | 0.84 | MMP2 (0.59) | MMP2MMP8MMP1MMP9MMP7 | |
| SCHEMBL8358360 | 0.84 | MMP2 (0.59) | MMP2MMP8MMP1MMP9MMP7 | |
| SCHEMBL8357549 | 0.83 | MMP8 (0.57) | MMP2MMP8MMP1MMP9MMP7 | |
| SCHEMBL14186805 | 0.82 | MMP2 (0.62) | MMP2MMP8MMP1CCKBRCCKAR | |
| SCHEMBL8242166 | 0.81 | MMP2 (0.63) | MMP2MMP8MMP1CCKBRCCKAR | |
| SCHEMBL29549543 | 0.81 | MAGI3 (0.56) | ERBB2IL23ROPRD1KISS1RMAGI3 | |
| SCHEMBL8245264 | 0.79 | MMP2 (0.58) | MMP2MMP8MMP1CCKBRCCKAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8129342-B2 | High purity lipopeptides | CUBIST PHARMACEUTICALS, INC. (US) | 2012-03-06 | — | — | US | disclosed |
| US-20110207658-A1 | High Purity Lipopeptides | CUBIST PHARMACEUTICALS LLC (CH) | 2011-08-25 | — | — | US | disclosed |