Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1B | P28222 | 5/20 | 0.47 |
| ▸ | HTR1D | P28221 | 2/20 | 0.47 |
| ▸ | CDYL | Q9Y232 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD1 | P21728 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.35 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.35 |
| ▸ | RAD52 | P43351 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8355802 | 0.83 | HTR1B (0.39) | HTR1BHTR1DDRD2DRD1DRD3 | |
| SCHEMBL8357744 | 0.82 | THRB (0.40) | HTR1BHTR1DDRD2DRD1DRD3 | |
| SCHEMBL8551954 | 0.81 | LMNA (0.50) | HTR1BHTR1DCDYLKDM4EPTPN1 | |
| SCHEMBL8356718 | 0.81 | THRB (0.39) | HTR1BHTR1DDRD2DRD1DRD3 | |
| SCHEMBL8361614 | 0.80 | HTR1B (0.46) | HTR1BHTR1DALDH1A1KDM4EMEN1 | |
| SCHEMBL8356222 | 0.79 | THRB (0.38) | HTR1BHTR1DDRD2DRD1DRD3 | |
| SCHEMBL8358531 | 0.74 | ALDH1A1 (0.48) | HTR1BHTR1DDRD2DRD1DRD3 | |
| SCHEMBL8357474 | 0.73 | LMNA (0.57) | HTR1BHTR1DCDYLKDM4EPTPN1 | |
| SCHEMBL8357765 | 0.71 | SCD (0.37) | ALDH1A1 | |
| SCHEMBL8359946 | 0.70 | THRB (0.42) | DRD2DRD1DRD3ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5919807-A | ANTICHOLESTEROL AGENTS | DR. KARL THOMAE GMBH (DE) | 1999-07-06 | — | — | US | disclosed |