Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | LSS | P48449 | 2/20 | 0.42 |
| ▸ | CDYL | Q9Y232 | 1/20 | 0.41 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HTR1D | P28221 | 1/20 | 0.39 |
| ▸ | HTR1B | P28222 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA4 | P22748 | 1/20 | 0.37 |
| ▸ | ATP4A | P20648 | 1/20 | 0.37 |
| ▸ | ATP4B | P51164 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8357474 | 0.93 | LMNA (0.57) | LMNACYP1A2CYP2D6CDYLALK | |
| SCHEMBL8552033 | 0.83 | LMNA (0.52) | LMNACYP1A2CYP2D6LSSALK | |
| SCHEMBL8358150 | 0.82 | RAB9A (0.41) | LMNACYP1A2CYP2D6KDM4ECA1 | |
| SCHEMBL8358024 | 0.81 | HTR1B (0.47) | CDYLKDM4EHTR1DHTR1BPTPN1 | |
| SCHEMBL8361490 | 0.80 | LMNA (0.53) | LMNACYP1A2CYP2D6LSSCA1 | |
| SCHEMBL8552900 | 0.80 | LMNA (0.53) | LMNACYP1A2CYP2D6LSSCA1 | |
| SCHEMBL8548836 | 0.79 | LMNA (0.56) | LMNACYP1A2CYP2D6LSSKDM4E | |
| SCHEMBL8550339 | 0.79 | LMNA (0.55) | LMNACYP1A2CYP2D6LSSCA1 | |
| SCHEMBL8358060 | 0.78 | LMNA (0.63) | LMNACYP1A2CYP2D6CA1CA2 | |
| SCHEMBL8551252 | 0.78 | LMNA (0.50) | LMNACYP1A2CYP2D6LSSCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0824529-A1 | BENZOTHIAZOLES AND BENZOXAZOLES, AS WELL AS DRUGS CONTAINING THEM, THEIR USE AND METHODS OF PREPARING THEM | Dr. Karl Thomae GmbH (DE) | 1998-02-25 | — | — | EP | disclosed |
| WO-1996035681-A1 | BENZOTHIAZOLES AND BENZOXAZOLES, AS WELL AS DRUGS CONTAINING THEM, THEIR USE AND METHODS OF PREPARING THEM | DR. KARL THOMAE GMBH (DE) | 1996-11-14 | — | — | WO | disclosed |