Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.32 |
| ▸ | ADH1B | P00325 | 1/20 | 0.31 |
| ▸ | ADH1C | P00326 | 1/20 | 0.31 |
| ▸ | ADH1A | P07327 | 1/20 | 0.31 |
| ▸ | ADH4 | P08319 | 1/20 | 0.31 |
| ▸ | ADH7 | P40394 | 1/20 | 0.31 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.31 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.31 |
| ▸ | GAPDH | P04406 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | FDPS | P14324 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8649835 | 0.96 | TSHR (0.44) | TSHRALDH1A1OPRM1LMNAPTGS1 | |
| SCHEMBL27311941 | 0.84 | TSHR (0.42) | TSHRALDH1A1OPRM1LMNAADH1B | |
| SCHEMBL16288370 | 0.82 | TSHR (0.46) | TSHRALDH1A1PTGS1PPARGOPRK1 | |
| SCHEMBL4023419 | 0.81 | TSHR (0.46) | TSHRALDH1A1OPRM1LMNAADH1B | |
| Water SCHEMBL8815837 | 0.81 | TSHR (0.40) | TSHRALDH1A1OPRM1LMNAADH1B | |
| SCHEMBL6336658 | 0.81 | TSHR (0.46) | TSHRALDH1A1OPRM1LMNAADH1B | |
| SCHEMBL4515246 | 0.81 | TSHR (0.46) | TSHRALDH1A1OPRM1LMNAADH1B | |
| SCHEMBL4530979 | 0.81 | TSHR (0.46) | TSHRALDH1A1OPRM1LMNAADH1B | |
| SCHEMBL6339666 | 0.81 | TSHR (0.46) | TSHRALDH1A1OPRM1LMNAADH1B | |
| SCHEMBL28274267 | 0.81 | TSHR (0.46) | TSHRALDH1A1OPRM1LMNAADH1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 202 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116199612-B | Porous adsorbent and preparation method and application thereof | 荆楚理工学院 | 2024-06-21 | — | — | CN | claimed |
| CN-116199612-A | Porous adsorbent and preparation method and application thereof | 荆楚理工学院 | 2023-06-02 | — | — | CN | claimed |
| CN-114907692-A | Phthalonitrile resin and preparation method and application thereof | 中国科学院化学研究所 | 2022-08-16 | — | — | CN | claimed |
| EP-3755687-B1 | ADDUCT BETWEEN A PYRROLIC COMPOUND AND AN INORGANIC OXIDE HYDROXIDE, A SUPER-ADDUCT BETWEEN A PYRROLIC COMPOUND, AN INORGANIC OXIDE HYDROXIDE AND A CARBON ALLOTROPE, ELASTOMERIC COMPOSITION COMPRISING THE SUPER-ADDUCT AND METHODS FOR PRODUCING THE SAME | PIRELLI (IT) | 2022-06-29 | — | — | EP | claimed |
| US-11091608-B2 | Elastomeric composition and vulcanization accelerator used therein | PIRELLI TYRE S.P.A. (IT) | 2021-08-17 | — | — | US | claimed |
| EP-3397678-B1 | ELASTOMERIC COMPOSITION AND VULCANIZATION ACCELERATOR USED THEREIN | PIRELLI (IT) | 2021-07-28 | — | — | EP | claimed |
| US-20210179821-A1 | ELASTOMERIC COMPOSITION AND VULCANIZATION ACCELERATOR USED THEREIN | PIRELLI TYRE S.P.A. (IT) | 2021-06-17 | — | — | US | claimed |
| US-20210167463-A1 | POLYMER-CERAMIC HYBRID SEPARATOR MEMBRANES, PRECURSORS, AND MANUFACTURING PROCESSES | CORNELL UNIVERSITY | 2021-06-03 | — | — | US | claimed |
| EP-3538511-B1 | ADDUCTS FORMED FROM PRIMARY AMINES, DICARBONYL DERIVATIVES, INORGANIC OXIDE HYDROXYDES AND SP2-HYBRIDIZED CARBON ALLOTROPES | PIRELLI (IT) | 2021-04-21 | — | — | EP | claimed |
| US-20200223797-A1 | ADDUCTS FORMED FROM PRIMARY AMINES, DICARBONYL DERIVATIVES, INORGANIC OXIDE HYDROXYDES AND SP2-HYBRIDIZED CARBON ALLOTROPES | PIRELLI TYRE S.P.A. (IT) | 2020-07-16 | — | — | US | claimed |
| EP-1740171-B1 | INDOL-1-YL-ACETIC ACID DERIVATIVES | ACTELION PHARMACEUTICALS LTD (CH) | 2010-06-09 | — | — | EP | claimed |
| US-7557212-B2 | Tricyclic derivatives as LTD4 antagonists | LABORATORIOS ALMIRALL, S.A. (ES) | 2009-07-07 | — | — | US | claimed |
| CN-100379742-C | novel tricyclic derivatives as LTD4 antagonists | ALMIRALL PRODESFARMA SA (ES) | 2008-04-09 | — | — | CN | claimed |
| US-20070208004-A1 | Indol-1-yl-acetic acid derivatives | ACTELION PHARMACEUTICALS, LTD. (CH) | 2007-09-06 | — | — | US | claimed |
| EP-1740171-A1 | INDOL-1-YL-ACETIC ACID DERIVATIVES | Actelion Pharmaceuticals Ltd. (CH) | 2007-01-10 | — | — | EP | claimed |
| US-20060116363-A1 | Tricyclic derivatives as ltd4 antagonists | LABORATORIOS ALMIRALL, S.A. (ES) | 2006-06-01 | — | — | US | claimed |
| CN-1735618-A | New tricyclic derivatives as LTD4 antagonists | ALMIRALL PRODESFARMA SA (ES) | 2006-02-15 | — | — | CN | claimed |
| WO-2005094816-A1 | INDOL-1-YL-ACETIC ACID DERIVATIVES | ACTELION PHARMACEUTICALS LTD (CH) | 2005-10-13 | — | — | WO | claimed |
| EP-1560834-A1 | NEW TRICYCLIC DERIVATIVES AS LTD4 ANTAGONISTS | Almirall Prodesfarma, S.A. (ES) | 2005-08-10 | — | — | EP | claimed |
| WO-2004043966-A1 | NEW TRICYCLIC DERIVATIVES AS LTD4 ANTAGONISTS | ALMIRALL PRODESFARMA S.A. (ES) | 2004-05-27 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060116363-A1 | Tricyclic derivatives as ltd4 antagonists | LTA4H, LTC4S, LTB4R2 | TSHR 2013/4885ALDH1A1 1149/4885OPRM1 544/4885 |
| US-20070208004-A1 | Indol-1-yl-acetic acid derivatives | IDO1, IDO2, AANAT | TSHR 3401/4885ALDH1A1 67/4885OPRM1 2914/4885 |
| US-20200223797-A1 | ADDUCTS FORMED FROM PRIMARY AMINES, DICARBONYL DERIVATIVES, INORGANIC OXIDE HYDROXYDES AND SP2-HYBRIDIZED CARBON ALLOTROPES | DRD4, DRD2, DAXX | TSHR 4387/4885ALDH1A1 1206/4885OPRM1 2285/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.