Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHAT | P28329 | 8/20 | 0.60 |
| ▸ | RAB9A | P51151 | 6/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.60 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.60 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | ALPG | P10696 | 1/20 | 0.54 |
| ▸ | THRB | P10828 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | GFER | P55789 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | USP2 | O75604 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2845206 | 0.83 | RELA (0.55) | CHATAPP | |
| SCHEMBL2845201 | 0.83 | RELA (0.55) | CHATAPP | |
| SCHEMBL29808641 | 0.82 | RELA (0.53) | CHATAPP | |
| SCHEMBL29523356 | 0.81 | GSK3B (0.44) | KDM4EMAPTALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL2776332 | 0.79 | APP (0.67) | RAB9AKDM4EMEN1KMT2AMAPT | |
| SCHEMBL2776337 | 0.79 | APP (0.67) | RAB9AKDM4EMEN1KMT2AMAPT | |
| Hydrochloric Acid SCHEMBL9052352 | 0.79 | CHAT (0.38) | CHATRAB9AKDM4EAPOBEC3AAPOBEC3G | |
| Bromide SCHEMBL8666503 | 0.77 | CHAT (0.40) | CHATRAB9AKDM4EAPOBEC3AAPOBEC3G | |
| SCHEMBL4072573 | 0.77 | MAPT (0.55) | RAB9AKDM4EMEN1KMT2AMAPT | |
| Iodide SCHEMBL8702272 | 0.76 | RAB9A (0.52) | CHATRAB9AKDM4EAPOBEC3AAPOBEC3G |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5856522-A | Method of using synthesis of 1,2-dioxetanes and kits therefore | TROPIX, INC. (US) | 1999-01-05 | — | — | US | disclosed |
| US-5777133-A | Synthesis of 1, 2-dioxetanes and intermediates therefor | TROPIX, INC. (US) | 1998-07-07 | — | — | US | disclosed |
| US-5679802-A | 1,2-dioxetanes useful in chemiluminescent immunoassays | TROPIX, INC. (US) | 1997-10-21 | — | — | US | disclosed |