Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | NPY1R | P25929 | 1/20 | 0.38 |
| ▸ | NPY2R | P49146 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8357459 | 0.85 | AGTR2 (0.36) | LMNAPPARG | |
| SCHEMBL8361975 | 0.85 | ALDH1A1 (0.36) | ALDH1A1LMNANPY1RNPY2RL3MBTL1 | |
| SCHEMBL8364418 | 0.81 | AGTR1 (0.44) | PPARG | |
| SCHEMBL8419023 | 0.80 | ALDH1A1 (0.36) | ALDH1A1PPARG | |
| SCHEMBL8364583 | 0.80 | AGTR1 (0.37) | PPARG | |
| SCHEMBL8359530 | 0.79 | AGTR1 (0.39) | PPARG | |
| SCHEMBL8364430 | 0.79 | PPARG (0.38) | PPARG | |
| SCHEMBL8417384 | 0.77 | PLA2G2A (0.36) | — | |
| SCHEMBL8711109 | 0.77 | AGTR2 (0.47) | PPARG | |
| SCHEMBL8421698 | 0.77 | AGTR1 (0.41) | PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5883111-A | STRONG AND LONG-LASTING ACTION BY ORAL ADMINISTRATION; HYPOTENSIVE AGENTS; CARDIOTONIC AGENTS; ALZHEIMER'S DISEASE; | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1999-03-16 | — | — | US | disclosed |
| US-5736555-A | HYPOTENSIVE AGENTS; FDA ORANGE BOOK LISTED PATENT FOR AZILSARTAN MEDOXOMIL | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-04-07 | — | — | US | disclosed |