Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRPF1 | P55201 | 10/20 | 0.46 |
| ▸ | BRD1 | O95696 | 3/20 | 0.46 |
| ▸ | BRPF3 | Q9ULD4 | 2/20 | 0.46 |
| ▸ | BRD9 | Q9H8M2 | 3/20 | 0.43 |
| ▸ | BRD4 | O60885 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | S100B | P04271 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17576630 | 0.77 | S100B (0.58) | BRPF1BRD1BRPF3BRD9BRD4 | |
| SCHEMBL6603697 | 0.75 | ALDH1A1 (0.47) | BRPF1BRD1BRPF3BRD9BRD4 | |
| SCHEMBL30665881 | 0.74 | BRPF1 (0.52) | BRPF1BRD1BRPF3BRD9BRD4 | |
| SCHEMBL17576626 | 0.74 | BRPF1 (0.52) | BRPF1BRD1BRPF3BRD9BRD4 | |
| SCHEMBL16432414 | 0.74 | BRPF1 (0.52) | BRPF1BRD1BRPF3BRD9BRD4 | |
| SCHEMBL9320188 | 0.70 | BRPF1 (0.62) | BRPF1BRD1BRPF3BRD9BRD4 | |
| SCHEMBL19231462 | 0.69 | CA2 (0.55) | BRPF1BRD9BRD4CA12CA9 | |
| SCHEMBL2761914 | 0.69 | TAAR1 (0.56) | GAATAAR1 | |
| SCHEMBL15345380 | 0.69 | NQO1 (0.50) | KDM4EALDH1A1HPGDTAAR1 | |
| SCHEMBL6074279 | 0.68 | BRPF1 (0.59) | BRPF1BRD1BRPF3BRD9BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003105815-A1 | COMBINATION OF PDE-V INHIBITORS AND NK1 ANTAGONISTS FOR THE TREATMENT OF DEPRESSION | PFIZER PRODUCTS INC. (US) | 2003-12-24 | — | — | WO | disclosed |