Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDIA6 | Q15084 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 5/20 | 0.38 |
| ▸ | CA2 | P00918 | 5/20 | 0.38 |
| ▸ | CA7 | P43166 | 2/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18098668 | 0.81 | L3MBTL1 (0.59) | PDIA6L3MBTL1ALDH1A1POLBMAPT | |
| SCHEMBL30266645 | 0.78 | PDIA6 (0.55) | PDIA6L3MBTL1ALDH1A1KDM4EMEN1 | |
| SCHEMBL5795116 | 0.78 | PDIA6 (0.55) | PDIA6L3MBTL1ALDH1A1KDM4EMEN1 | |
| SCHEMBL23536145 | 0.77 | PDIA6 (0.53) | PDIA6L3MBTL1KDM4EMEN1MAPT | |
| SCHEMBL1807019 | 0.77 | L3MBTL1 (0.70) | PDIA6L3MBTL1ALDH1A1KDM4EMEN1 | |
| SCHEMBL3781004 | 0.77 | CA2 (0.50) | ALDH1A1KDM4ETET2CA1CA2 | |
| SCHEMBL1808292 | 0.77 | PDIA6 (0.53) | PDIA6L3MBTL1ALDH1A1KDM4EMEN1 | |
| SCHEMBL12094098 | 0.77 | PDIA6 (0.53) | PDIA6L3MBTL1ALDH1A1KDM4EMEN1 | |
| SCHEMBL1807162 | 0.76 | PDIA6 (0.53) | PDIA6L3MBTL1ALDH1A1KDM4ELMNA | |
| SCHEMBL3257803 | 0.76 | CA2 (0.38) | PDIA6ALDH1A1KDM4ETET2CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003026652-A1 | LACTAM-CONTAINING COMPOUNDS AND DERIVATIVES THEREOF AS FACTOR XA INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2003-04-03 | — | — | WO | disclosed |