Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 5/20 | 0.38 |
| ▸ | MAPK13 | O15264 | 2/20 | 0.37 |
| ▸ | MAPK12 | P53778 | 2/20 | 0.37 |
| ▸ | MAPK11 | Q15759 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | SRC | P12931 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.34 |
| ▸ | PDE11A | Q9HCR9 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8287991 | 0.90 | GAA (0.39) | GAAGFERMAPTMAPK1HPGD | |
| SCHEMBL8287257 | 0.87 | RAB9A (0.40) | GAAMAPTMAPK1HPGDNPC1 | |
| SCHEMBL8362709 | 0.85 | PDE11A (0.39) | GAAGFERMAPTMAPK1HPGD | |
| SCHEMBL8287252 | 0.85 | CXCR2 (0.37) | GAAGFERMAPTMAPK1HPGD | |
| SCHEMBL8287253 | 0.84 | RIPK1 (0.43) | MAPK14MAPTNPC1RAB9AHTT | |
| SCHEMBL8287988 | 0.82 | CSF1R (0.47) | GAAMAPTHPGDSMN1; SMN2HTT | |
| SCHEMBL8287258 | 0.82 | GRM5 (0.45) | GAAMAPTMAPK1HPGDSMN1; SMN2 | |
| SCHEMBL8360822 | 0.81 | CSF1R (0.37) | MAPK14MAPTHPGDPDE11ASMN1; SMN2 | |
| SCHEMBL8287246 | 0.81 | GAA (0.39) | GAAGFERMAPTSRCMAPK1 | |
| SCHEMBL8285367 | 0.81 | KCNJ6 (0.37) | MAPK14MAPK13MAPK12MAPK11GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003027112-A1 | 1, 8-NAPHTHYRIDINE DERIVATIVES AS ANTIDIABETICS | BAYER PHARMACEUTICALS CORPORATION (US) | 2003-04-03 | — | — | WO | disclosed |