Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.34 |
| ▸ | PRKDC | P78527 | 1/20 | 0.34 |
| ▸ | PDE11A | Q9HCR9 | 1/20 | 0.33 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.33 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | SLC5A1 | P13866 | 3/20 | 0.33 |
| ▸ | CDK4 | P11802 | 2/20 | 0.33 |
| ▸ | CCND1 | P24385 | 2/20 | 0.33 |
| ▸ | CCND2 | P30279 | 2/20 | 0.33 |
| ▸ | CCND3 | P30281 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8287991 | 0.84 | GAA (0.39) | CSF1RMAPTHPGDPDE11ACDK4 | |
| SCHEMBL8287258 | 0.83 | GRM5 (0.45) | CSF1RMAPTHPGDGRM5ALDH1A1 | |
| SCHEMBL8287253 | 0.83 | RIPK1 (0.43) | MAPTRXFP1CNR2MAPK14 | |
| SCHEMBL8287262 | 0.82 | HSD11B1 (0.46) | MAPTRXFP1HPGDPDE11ASLC5A1 | |
| SCHEMBL8360854 | 0.81 | MAPK14 (0.38) | MAPTHPGDPDE11AMAPK14CDK4 | |
| SCHEMBL8287257 | 0.81 | RAB9A (0.40) | MAPTHPGDTP53ALDH1A1SMN1; SMN2 | |
| SCHEMBL8361774 | 0.81 | RIPK1 (0.42) | CNR2MAPK14ALDH1A1 | |
| SCHEMBL8287277 | 0.80 | AOC3 (0.39) | MAPTRXFP1PDE11ATP53CDK4 | |
| SCHEMBL8362709 | 0.80 | PDE11A (0.39) | CSF1RMAPTHPGDPDE11ATP53 | |
| SCHEMBL8287252 | 0.80 | CXCR2 (0.37) | CSF1RMAPTHPGDPDE11ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003027112-A1 | 1, 8-NAPHTHYRIDINE DERIVATIVES AS ANTIDIABETICS | BAYER PHARMACEUTICALS CORPORATION (US) | 2003-04-03 | — | — | WO | disclosed |