Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE11A | Q9HCR9 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8287270 | 0.85 | HSD11B1 (0.40) | PDE11A | |
| SCHEMBL8286455 | 0.84 | PLA2G4A (0.37) | PDE11A | |
| SCHEMBL8287273 | 0.82 | PDE11A (0.34) | PDE11A | |
| SCHEMBL8287259 | 0.82 | GAA (0.34) | PDE11A | |
| SCHEMBL8286560 | 0.82 | MAPT (0.39) | — | |
| SCHEMBL8286552 | 0.81 | CCNC (0.37) | PDE11A | |
| SCHEMBL8287263 | 0.81 | TSHR (0.40) | PDE11A | |
| SCHEMBL8286557 | 0.80 | NPC1 (0.40) | PDE11A | |
| SCHEMBL8287264 | 0.80 | PDE11A (0.31) | PDE11A | |
| SCHEMBL8287262 | 0.79 | HSD11B1 (0.46) | PDE11A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003027112-A1 | 1, 8-NAPHTHYRIDINE DERIVATIVES AS ANTIDIABETICS | BAYER PHARMACEUTICALS CORPORATION (US) | 2003-04-03 | — | — | WO | disclosed |