Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 3/20 | 1.00 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | IDO1 | P14902 | 1/20 | 0.48 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.47 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.47 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.47 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.47 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.47 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.47 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.47 |
| ▸ | PHGDH | O43175 | 1/20 | 0.46 |
| ▸ | DAO | P14920 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30604651 | 0.93 | SLC9A1 (0.86) | SLC9A1MCL1MAPTMEN1NPC1 | |
| SCHEMBL2323444 | 0.82 | MCL1 (0.71) | SLC9A1MCL1MAPTMEN1NPC1 | |
| Hydrochloric Acid SCHEMBL28264080 | 0.80 | MCL1 (0.69) | SLC9A1MCL1MAPTMEN1NPC1 | |
| SCHEMBL10031558 | 0.79 | MCL1 (0.67) | SLC9A1MCL1MAPTMEN1NPC1 | |
| SCHEMBL16599480 | 0.78 | MCL1 (0.76) | SLC9A1MCL1MAPTMEN1NPC1 | |
| SCHEMBL401039 | 0.76 | MCL1 (0.73) | SLC9A1MCL1MAPTMEN1NPC1 | |
| SCHEMBL117186 | 0.76 | MCL1 (1.00) | SLC9A1MCL1MAPTMEN1NPC1 | |
| SCHEMBL7268278 | 0.76 | SLC9A1 (0.60) | SLC9A1MCL1MAPTMEN1NPC1 | |
| Guanidine SCHEMBL8688091 | 0.75 | MCL1 (0.81) | SLC9A1MCL1MAPTMEN1NPC1 | |
| SCHEMBL2322980 | 0.75 | MCL1 (0.71) | SLC9A1MCL1MAPTMEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090143473-A1 | USE OF INHIBITORS OF THE CELLULAR NA+/H+ EXCHANGER (NHE) FOR PREPARING A MEDICAMENT FOR NORMALIZING SERUM LIPIDS | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2009-06-04 | — | — | US | disclosed |
| WO-2003068212-A1 | USE OF SODIUM/HYDROGEN EXCHANGE INHIBITORS FROM THE TREATMENT OF THROMBOTIC AND INFLAMMATORY DISEASES | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2003-08-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090143473-A1 | USE OF INHIBITORS OF THE CELLULAR NA+/H+ EXCHANGER (NHE) FOR PREPARING A MEDICAMENT FOR NORMALIZING SERUM LIPIDS | NHERF1, LIPG, SLC8B1 | SLC9A1 8/4885MCL1 3434/4885MAPT 3998/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.