Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 1/20 | 0.59 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.59 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.59 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | PKM | P14618 | 1/20 | 0.58 |
| ▸ | CA2 | P00918 | 2/20 | 0.53 |
| ▸ | MMP2 | P08253 | 2/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | MMP1 | P03956 | 1/20 | 0.53 |
| ▸ | MMP9 | P14780 | 1/20 | 0.53 |
| ▸ | MMP8 | P22894 | 1/20 | 0.53 |
| ▸ | MMP13 | P45452 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.51 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.51 |
| ▸ | PGR | P06401 | 1/20 | 0.49 |
| ▸ | DDX3X | O00571 | 1/20 | 0.49 |
| ▸ | KDM1A | O60341 | 1/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6834397 | 0.97 | CASP3 (0.58) | CASP3SENP8SENP7SENP6KMT2A | |
| SCHEMBL6834395 | 0.97 | CASP3 (0.58) | CASP3SENP8SENP7SENP6KMT2A | |
| SCHEMBL7066283 | 0.97 | CASP3 (0.58) | CASP3SENP8SENP7SENP6KMT2A | |
| SCHEMBL8366106 | 0.83 | CASP3 (0.81) | CASP3SENP8SENP7SENP6KMT2A | |
| SCHEMBL6834286 | 0.82 | ITGA1 (0.65) | KMT2AALDH1A1HSD17B1HSD17B2POLB | |
| SCHEMBL6834188 | 0.81 | HDAC1 (0.60) | KMT2APKMALDH1A1POLBGAA | |
| SCHEMBL6833577 | 0.80 | L3MBTL1 (0.59) | PKMCA2MMP2CA1MMP1 | |
| SCHEMBL6205956 | 0.80 | CASP3 (0.61) | CASP3SENP8SENP7SENP6KMT2A | |
| SCHEMBL6205953 | 0.80 | CASP3 (0.61) | CASP3SENP8SENP7SENP6KMT2A | |
| SCHEMBL6205955 | 0.80 | CASP3 (0.61) | CASP3SENP8SENP7SENP6KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040029928-A1 | Novel propenohydroxamic acid derivatives | WAKUNAGA PHARMACEUTICAL CO., LTD. (JP) | 2004-02-12 | — | — | US | disclosed |
| EP-1314721-A1 | NOVEL PROPENOHYDROXAMIC ACID DERIVATIVES | WAKUNAGA PHARMACEUTICAL CO., LTD. (JP) | 2003-05-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040029928-A1 | Novel propenohydroxamic acid derivatives | TNF, SI, HDGF | CASP3 386/4885SENP8 3015/4885SENP7 2046/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.