Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.60 |
| ▸ | SRD5A2 | P31213 | 5/20 | 0.58 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.51 |
| ▸ | FEN1 | P39748 | 1/20 | 0.51 |
| ▸ | CES2 | O00748 | 2/20 | 0.50 |
| ▸ | CES1 | P23141 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | PGR | P06401 | 1/20 | 0.49 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.48 |
| ▸ | LTA4H | P09960 | 2/20 | 0.48 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.48 |
| ▸ | BAX | Q07812 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.48 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.48 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.48 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15059492 | 0.88 | PARP10 (0.60) | PARP10SRD5A2ERCC5FEN1CES2 | |
| SCHEMBL4189871 | 0.87 | PARP10 (0.69) | PARP10SRD5A2ERCC5FEN1CES2 | |
| SCHEMBL9242631 | 0.85 | CES2 (0.68) | PARP10SRD5A2ERCC5FEN1CES2 | |
| SCHEMBL21786 | 0.83 | PARP10 (0.64) | PARP10SRD5A2ERCC5FEN1SMN1; SMN2 | |
| SCHEMBL9807208 | 0.83 | PARP10 (0.64) | PARP10SRD5A2ERCC5FEN1CES2 | |
| SCHEMBL9249310 | 0.83 | PARP10 (0.64) | PARP10SRD5A2ERCC5FEN1SMN1; SMN2 | |
| SCHEMBL4166171 | 0.83 | PARP10 (0.64) | PARP10SRD5A2ERCC5FEN1CES2 | |
| SCHEMBL2134251 | 0.83 | CES2 (0.71) | PARP10SRD5A2ERCC5FEN1CES2 | |
| SCHEMBL13567254 | 0.83 | CES2 (0.71) | PARP10SRD5A2ERCC5FEN1CES2 | |
| SCHEMBL9250736 | 0.83 | CES2 (0.71) | PARP10SRD5A2ERCC5FEN1CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-11002899-A | — | — | None | — | — | JP | disclosed |
| JP-H112899-A | NEGATIVE RADIATION SENSITIVE RESIST COMPOSITION AND THESE HARDENED PRODUCT | NIPPON KAYAKU CO LTD | 1999-01-06 | — | — | JP | disclosed |