Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | GUCY1B2 | O75343 | 1/20 | 0.55 |
| ▸ | GUCY1A2 | P33402 | 1/20 | 0.55 |
| ▸ | GUCY1A1 | Q02108 | 1/20 | 0.55 |
| ▸ | GUCY1B1 | Q02153 | 1/20 | 0.55 |
| ▸ | CDK4 | P11802 | 8/20 | 0.55 |
| ▸ | BLM | P54132 | 4/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | HTT | P42858 | 3/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.53 |
| ▸ | CASP3 | P42574 | 3/20 | 0.53 |
| ▸ | SENP8 | Q96LD8 | 3/20 | 0.53 |
| ▸ | SENP7 | Q9BQF6 | 3/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8370522 | 0.87 | CDK4 (0.57) | MAPTSMN1; SMN2TDP1MEN1KMT2A | |
| SCHEMBL8367064 | 0.84 | CDK4 (0.62) | MAPTSMN1; SMN2TDP1MEN1KMT2A | |
| SCHEMBL8368953 | 0.81 | SMN1; SMN2 (0.59) | MAPTSMN1; SMN2TDP1MEN1KMT2A | |
| SCHEMBL8368653 | 0.78 | MAPT (0.70) | MAPTSMN1; SMN2TDP1MEN1KMT2A | |
| SCHEMBL14067780 | 0.73 | TDP1 (0.48) | MAPTTDP1MEN1KMT2AALDH1A1 | |
| SCHEMBL8371613 | 0.72 | CDK4 (0.62) | MAPTSMN1; SMN2TDP1MEN1KMT2A | |
| SCHEMBL8369531 | 0.72 | CASP3 (0.51) | MAPTSMN1; SMN2TDP1MEN1KMT2A | |
| SCHEMBL8370506 | 0.72 | MAPT (0.51) | MAPTSMN1; SMN2TDP1MEN1KMT2A | |
| SCHEMBL8653696 | 0.72 | MAPT (0.62) | MAPTSMN1; SMN2TDP1MEN1KMT2A | |
| SCHEMBL755665 | 0.71 | MAPT (0.64) | MAPTSMN1; SMN2TDP1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999052365-A1 | ANTICANCER AGENTS | ELI LILLY AND COMPANY (US) | 1999-10-21 | — | — | WO | disclosed |