SCHEMBL836808

SCHEMBL836808

CC(C)(C)OC(=O)C(=O)Cl

nearest known ligand 0.39

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
DGAT1 O75907 1/20 0.39
CHRM2 P08172 1/20 0.33
CHRM1 P11229 1/20 0.33
CHRM3 P20309 1/20 0.33
USP2 O75604 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
NR1H2 P55055 1/20 0.31
ELANE P08246 1/20 0.30
TDP1 Q9NUW8 1/20 0.30
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL78520 0.81 DGAT1 (0.46) DGAT1CHRM2CHRM1CHRM3USP2
SCHEMBL31458678 0.79 DGAT1 (0.40) DGAT1CHRM2CHRM1CHRM3USP2
SCHEMBL5408152 0.78 DGAT1 (0.36) DGAT1CHRM2CHRM1CHRM3ALDH1A1
SCHEMBL27463948 0.78 DGAT1 (0.36) DGAT1CHRM2CHRM1CHRM3NR1H2
SCHEMBL29399642 0.78
SCHEMBL19041123 0.76 PPARA (0.36) ALDH1A1
SCHEMBL11621321 0.75 DGAT1 (0.42) DGAT1CHRM2CHRM1CHRM3USP2
SCHEMBL79871 0.75
Hydrazine SCHEMBL10794464 0.75 DGAT1 (0.42) DGAT1CHRM2CHRM1CHRM3USP2
SCHEMBL15108015 0.75 DGAT1 (0.42) DGAT1CHRM2CHRM1CHRM3USP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 305 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103059046-B Preparation method of faropenem SUZHOU ERYE PHARMACEUTICAL CO 2015-01-07 CN claimed
CN-103059046-A Preparation method of faropenem SUZHOU ERYE PHARMACEUTICAL CO 2013-04-24 CN claimed
US-12617789-B2 Small molecular inhibitors of NF-κb inducing kinase JANSSEN PHARMACEUTICA NV (BE) 2026-05-05 US disclosed
US-20260035357-A1 THERAPEUTIC COMPOUNDS FOR HIV VIRUS INFECTION GILEAD SCIENCE INC (US) 2026-02-05 US disclosed
US-20250367166-A1 NEXT GENERATION DIPROVOCIMS THAT ACTIVATE THE INNATE AND ADAPTIVE IMMUNE RESPONSE SCRIPPS RESEARCH INST (US) 2025-12-04 US disclosed
US-12404262-B2 Therapeutic compounds for HIV virus infection GILEAD SCIENCES, INC. (US) 2025-09-02 US disclosed
EP-4566608-A2 THERAPEUTIC COMPOUNDS FOR HIV VIRUS INFECTION Gilead Sciences, Inc. (US) 2025-06-11 EP disclosed
US-20250179102-A1 THERAPEUTICS COMPOUNDS FOR HIV VIRUS INFECTION GILEAD SCIENCES, INC. 2025-06-05 US disclosed
EP-4440702-B1 THERAPEUTIC COMPOUNDS FOR HIV VIRUS INFECTION GILEAD SCIENCES INC (US) 2025-05-21 EP disclosed
EP-4445900-B1 THERAPEUTIC COMPOUNDS FOR HIV VIRUS INFECTION GILEAD SCIENCES INC (US) 2025-05-21 EP disclosed
US-12187753-B2 Therapeutics compounds for HIV virus infection GILEAD SCIENCES, INC. (US) 2025-01-07 US disclosed
EP-0378429-A2 Polymerisable compound and polymer therefrom NIPPON PAINT CO., LTD. (JP) 1990-07-18 EP disclosed
US-4940718-A BACTERICIDES ELI LILLY AND COMPANY (US) 1990-07-10 US disclosed
EP-0310214-A2 7-Substituted bicyclic pyrazolidinones ELI LILLY AND COMPANY (US) 1989-04-05 EP disclosed
US-4697033-A INSECTICIDES SANDOZ LTD. (CH) 1987-09-29 US disclosed
EP-0095860-B1 POLYMERISATION OF VINYL CHLORIDE MONOMER ICI AUSTRALIA LIMITED (AU) 1986-10-01 EP disclosed
US-4455412-A LOW TEMPERATURE, VINYL CHLORIDE ICI AUSTRALIA LIMITED (AU) 1984-06-19 US disclosed
EP-0095860-A2 Polymerisation of vinyl chloride monomer ICI AUSTRALIA LIMITED (AU) 1983-12-07 EP disclosed
US-4113880-A ANTIALLERGENS THE UPJOHN COMPANY (US) 1978-09-12 US disclosed
US-3941821-A ANTIINFLAMMATORY, ANALGESICS, ANTIPYRETICS WILLIAM H. RORER, INC. (US) 1976-03-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250179102-A1 THERAPEUTICS COMPOUNDS FOR HIV VIRUS INFECTION CD4, HAVCR2, MAVS DGAT1 1104/4885CHRM2 4705/4885CHRM1 4726/4885
US-12187753-B2 Therapeutics compounds for HIV virus infection CD4, HAVCR2, MAVS DGAT1 1104/4885CHRM2 4705/4885CHRM1 4726/4885
US-12404262-B2 Therapeutic compounds for HIV virus infection HAVCR2, MAVS, CD4 DGAT1 1401/4885CHRM2 4598/4885CHRM1 4618/4885
US-12617789-B2 Small molecular inhibitors of NF-κb inducing kinase IRAK3, IKBKB, IKBKG DGAT1 988/4885CHRM2 4790/4885CHRM1 4747/4885
US-20250367166-A1 NEXT GENERATION DIPROVOCIMS THAT ACTIVATE THE INNATE AND ADAPTIVE IMMUNE RESPONSE TLR1, TLR4, TLR3 DGAT1 2735/4885CHRM2 182/4885CHRM1 75/4885
US-20260035357-A1 THERAPEUTIC COMPOUNDS FOR HIV VIRUS INFECTION CCR10, CCR1, CCR3 DGAT1 1321/4885CHRM2 2831/4885CHRM1 1680/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.