Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.34 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.31 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9827534 | 0.82 | CDK1 (0.37) | KDM4EALDH1A1HPGDADRA1AHSD17B10 | |
| SCHEMBL8369323 | 0.78 | KDM4E (0.55) | KDM4EALDH1A1HPGDADRA1AHSD17B10 | |
| SCHEMBL9828688 | 0.77 | MEN1 (0.49) | ALDH1A1HSD17B10 | |
| SCHEMBL9827211 | 0.75 | ALDH1A1 (0.62) | KDM4EALDH1A1HPGDADRA1AHSD17B10 | |
| SCHEMBL9827214 | 0.73 | KDM4E (0.49) | KDM4EALDH1A1HPGDADRA1AHSD17B10 | |
| SCHEMBL9186857 | 0.72 | ALDH1A1 (0.53) | KDM4EALDH1A1HPGDADRA1AHSD17B10 | |
| SCHEMBL8926305 | 0.72 | HSD17B10 (0.61) | KDM4EALDH1A1HPGDADRA1AHSD17B10 | |
| SCHEMBL10645986 | 0.70 | ALDH1A1 (0.69) | KDM4EALDH1A1HPGDADRA1AHSD17B10 | |
| SCHEMBL8933939 | 0.70 | KDM4E (0.42) | KDM4EALDH1A1HPGDADRA1AHSD17B10 | |
| SCHEMBL10535574 | 0.70 | RXFP1 (0.74) | KDM4EALDH1A1HPGDADRA1AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0217207-B1 | 2-AMINO PURINES SUBSTITUTED IN POSITIONS 6 AND 9, THEIR USE, MEDICAMENTS CONTAINING THESE PURINES AND PROCESSES FOR THEIR PREPARATION | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-04-10 | — | — | EP | claimed |
| EP-0217207-B1 | 2-AMINO PURINES SUBSTITUTED IN POSITIONS 6 AND 9, THEIR USE, MEDICAMENTS CONTAINING THESE PURINES AND PROCESSES FOR THEIR PREPARATION | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-04-10 | — | — | EP | disclosed |
| EP-0400686-A1 | 2-Amino-9-[1,3bis-(isopropoxy)-propyl-2-oxymethyl]-purine, its utilization and medicaments containing it | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-12-05 | — | — | EP | disclosed |